Cybersecurity Analytics is for the cybersecurity student and professional who wants to learn data science techniques critical for tackling cybersecurity challenges, and for the data science student and professional who wants to learn about cybersecurity adaptations. Trying to build a malware detector, a phishing email detector, or just interested in finding patterns in your datasets? This book can let you do it on your own. Numerous examples and datasets links are included so that the reader can "learn by doing." Anyone with a basic college-level calculus course and some probability knowledge can easily understand most of the material. The book includes chapters containing: unsupervised learning, semi-supervised learning, supervised learning, text mining, natural language processing, and more. It also includes background on security, statistics, and linear algebra. The website for the book contains a listing of datasets, updates, and other resources for serious practitioners.

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these strategies are generally being considered on an individual trial basis and not as part of a fully integrated overall development program. Such optimization at the trial level is somewhat near-sighted and does not ensure cost, time, or development efficiency of the overall program. This book seeks to address this imbalance by establishing a statistical framework for overall/global clinical development optimization and providing tactics and techniques to support such optimization, including clinical trial simulations. Provides a statistical framework for achieve global optimization in each phase of the drug development process. Describes specific techniques to support optimization including adaptive designs, precision medicine, survival-endpoints, dose finding and multiple testing. Gives practical approaches to handling missing data in clinical trials using SAS. Looks at key controversial issues from both a clinical and statistical perspective. Presents a generous number of case studies from multiple therapeutic areas that help motivate and illustrate the statistical methods introduced in the book. Puts great emphasis on software implementation of the statistical methods with multiple examples of software code (both SAS and R). It is important for statisticians to possess a deep knowledge of the drug development process beyond statistical considerations. For these reasons, this book incorporates both statistical and "clinical/medical" perspectives.

This series has been developed specifically for the Cambridge International AS & A Level Mathematics (9709) syllabus to be examined from 2020. This title offers additional practice exercises for students following the Probability & Statistics 1 unit of the Cambridge International AS & A Level Mathematics syllabus (9709). The materials follow the same order as the corresponding coursebook and contain extra worked examples to help students understand the skills required of the syllabus. End-of-chapter review exercises are also provided to help students conduct self assessment, with answers at the back of the book to check understanding.

Geometric Data Analysis designates the approach of Multivariate Statistics that conceptualizes the set of observations as a Euclidean cloud of points. Combinatorial Inference in Geometric Data Analysis gives an overview of multidimensional statistical inference methods applicable to clouds of points that make no assumption on the process of generating data or distributions, and that are not based on random modelling but on permutation procedures recasting in a combinatorial framework. It focuses particularly on the comparison of a group of observations to a reference population (combinatorial test) or to a reference value of a location parameter (geometric test), and on problems of homogeneity, that is the comparison of several groups for two basic designs. These methods involve the use of combinatorial procedures to build a reference set in which we place the data. The chosen test statistics lead to original extensions, such as the geometric interpretation of the observed level, and the construction of a compatibility region. Features: Defines precisely the object under study in the context of multidimensional procedures, that is clouds of points Presents combinatorial tests and related computations with R and Coheris SPAD software Includes four original case studies to illustrate application of the tests Includes necessary mathematical background to ensure it is self-contained This book is suitable for researchers and students of multivariate statistics, as well as applied researchers of various scientific disciplines. It could be used for a specialized course taught at either master or PhD level.

A Computational Approach to Statistical Learning gives a novel introduction to predictive modeling by focusing on the algorithmic and numeric motivations behind popular statistical methods. The text contains annotated code to over 80 original reference functions. These functions provide minimal working implementations of common statistical learning algorithms. Every chapter concludes with a fully worked out application that illustrates predictive modeling tasks using a real-world dataset. The text begins with a detailed analysis of linear models and ordinary least squares. Subsequent chapters explore extensions such as ridge regression, generalized linear models, and additive models. The second half focuses on the use of general-purpose algorithms for convex optimization and their application to tasks in statistical learning. Models covered include the elastic net, dense neural networks, convolutional neural networks (CNNs), and spectral clustering. A unifying theme throughout the text is the use of optimization theory in the description of predictive models, with a particular focus on the singular value decomposition (SVD). Through this theme, the computational approach motivates and clarifies the relationships between various predictive models. Taylor Arnold is an assistant professor of statistics at the University of Richmond. His work at the intersection of computer vision, natural language processing, and digital humanities has been supported by multiple grants from the National Endowment for the Humanities (NEH) and the American Council of Learned Societies (ACLS). His first book, Humanities Data in R, was published in 2015. Michael Kane is an assistant professor of biostatistics at Yale University. He is the recipient of grants from the National Institutes of Health (NIH), DARPA, and the Bill and Melinda Gates Foundation. His R package bigmemory won the Chamber's prize for statistical software in 2010. Bryan Lewis is an applied mathematician and author of many popular R packages, including irlba, doRedis, and threejs.

This text bridges the gap between sound theoretcial developments and practical, fruitful methodology by providing solid justification for standard symptotic statistical methods. It contains a unified survey of standard large sample theory and provides access to more complex statistical models that arise in diverse practical applications.

Companion Website materials: https://tzkeith.com/ Multiple Regression and Beyond offers a conceptually-oriented introduction to multiple regression (MR) analysis and structural equation modeling (SEM), along with analyses that flow naturally from those methods. By focusing on the concepts and purposes of MR and related methods, rather than the derivation and calculation of formulae, this book introduces material to students more clearly, and in a less threatening way. In addition to illuminating content necessary for coursework, the accessibility of this approach means students are more likely to be able to conduct research using MR or SEM--and more likely to use the methods wisely. This book: * Covers both MR and SEM, while explaining their relevance to one another * Includes path analysis, confirmatory factor analysis, and latent growth modeling * Makes extensive use of real-world research examples in the chapters and in the end-of-chapter exercises * Extensive use of figures and tables providing examples and illustrating key concepts and techniques New to this edition: * New chapter on mediation, moderation, and common cause * New chapter on the analysis of interactions with latent variables and multilevel SEM * Expanded coverage of advanced SEM techniques in chapters 18 through 22 * International case studies and examples * Updated instructor and student online resources

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as supportive R tools, to evaluate and select among simultaneous competing designs or analysis options. It is applicable broadly to statisticians and other quantitative clinical trialists, who have an interest in optimizing clinical trials, clinical trial programs, or associated analytics and decision making. This book presents in depth the Clinical Scenario Evaluation (CSE) framework, and discusses optimization strategies, including the quantitative assessment of tradeoffs. A variety of common development challenges are evaluated as case studies, and used to show how this framework both simplifies and optimizes strategy selection. Specific settings include optimizing adaptive designs, multiplicity and subgroup analysis strategies, and overall development decision-making criteria around Go/No-Go. After this book, the reader will be equipped to extend the CSE framework to their particular development challenges as well.

A step-by-step guide for anyone challenged by the many subtleties of sampling particulate materials. The only comprehensive document merging the famous works of P. Gy, I. Visman, and C.O. Ingamells into a single theory in a logical way - the most advanced book on sampling that can be used by all sampling practitioners around the world.

- Includes industrial case studies - Includes chapters on cyber physical systems, machine learning, deep learning, cyber security, robotics, smart manufacturing and predictive analytics - surveys current trends and challenges in metaheuristics and industry 4.0

Originally published in 1995, Large Deviations for Performance Analysis consists of two synergistic parts. The first half develops the theory of large deviations from the beginning, through recent results on the theory for processes with boundaries, keeping to a very narrow path: continuous-time, discrete-state processes. By developing only what is needed for the applications, the theory is kept to a manageable level, both in terms of length and in terms of difficulty. Within its scope, the treatment is detailed, comprehensive and self-contained. As the book shows, there are sufficiently many interesting applications of jump Markov processes to warrant a special treatment. The second half is a collection of applications developed at Bell Laboratories. The applications cover large areas of the theory of communication networks: circuit switched transmission, packet transmission, multiple access channels, and the M/M/1 queue. Aspects of parallel computation are covered as well including, basics of job allocation, rollback-based parallel simulation, assorted priority queueing models that might be used in performance models of various computer architectures, and asymptotic coupling of processors. These applications are thoroughly analysed using the tools developed in the first half of the book.

A core task in statistical analysis, especially in the era of Big Data, is the fitting of flexible, high-dimensional, and non-linear models to noisy data in order to capture meaningful patterns. This can often result in challenging non-linear and non-convex global optimization problems. The large data volume that must be handled in Big Data applications further increases the difficulty of these problems. Swarm Intelligence Methods for Statistical Regression describes methods from the field of computational swarm intelligence (SI), and how they can be used to overcome the optimization bottleneck encountered in statistical analysis. Features Provides a short, self-contained overview of statistical data analysis and key results in stochastic optimization theory Focuses on methodology and results rather than formal proofs Reviews SI methods with a deeper focus on Particle Swarm Optimization (PSO) Uses concrete and realistic data analysis examples to guide the reader Includes practical tips and tricks for tuning PSO to extract good performance in real world data analysis challenges

Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making, ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap between theoretical statistical methods and practical procedures applied to the planning and analysis of health-related experiments. The book is organized primarily based on the type of questions to be answered by inference procedures or according to the general type of mathematical derivation. It establishes the theoretical framework for each method, with a substantial amount of chapter notes included for additional reference. It then focuses on the practical application for each concept, providing real-world examples that can be easily implemented using corresponding statistical software code in R and SAS. The book also explains the basic elements and methods for constructing correct and powerful statistical decision-making processes to be adapted for complex statistical applications. With techniques spanning robust statistical methods to more computationally intensive approaches, this book shows how to apply correct and efficient testing mechanisms to various problems encountered in medical and epidemiological studies, including clinical trials. Theoretical statisticians, medical researchers, and other practitioners in epidemiology and clinical research will appreciate the book's novel theoretical and applied results. The book is also suitable for graduate students in biostatistics, epidemiology, health-related sciences, and areas pertaining to formal decision-making mechanisms.

Twenty-four million people wager nearly $3 billion on college basketball pools each year, but few are aware that winning strategies have been developed by researchers at Harvard, Yale, and other universities over the past two decades. Bad advice from media sources and even our own psychological inclinations are often a bigger obstacle to winning than our pool opponents. Profit opportunities are missed and most brackets submitted to pools don't have a breakeven chance to win money before the tournament begins. Improving Your NCAA (R) Bracket with Statistics is both an easy-to-use tip sheet to improve your winning odds and an intellectual history of how statistical reasoning has been applied to the bracket pool using standard and innovative methods. It covers bracket improvement methods ranging from those that require only the information in the seeded bracket to sophisticated estimation techniques available via online simulations. Included are: Prominently displayed bracket improvement tips based on the published research A history of the origins of the bracket pool A history of bracket improvement methods and their results in play Historical sketches and background information on the mathematical and statistical methods that have been used in bracket analysis A source list of good bracket pool advice available each year that seeks to be comprehensive Warnings about common bad advice that will hurt your chances Tom Adams' work presenting bracket improvement methods has been featured in the New York Times, Sports Illustrated, and SmartMoney magazine.

Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to commercialization. It presents the theories and methods needed to carry out computer simulations efficiently, covers both descriptive and pseudocode algorithms that provide the basis for implementation of the simulation methods, and illustrates real-world problems through case studies. The text first emphasizes the importance of analogy and simulation using examples from a variety of areas, before introducing general sampling methods and the different stages of drug development. It then focuses on simulation approaches based on game theory and the Markov decision process, simulations in classical and adaptive trials, and various challenges in clinical trial management and execution. The author goes on to cover prescription drug marketing strategies and brand planning, molecular design and simulation, computational systems biology and biological pathway simulation with Petri nets, and physiologically based pharmacokinetic modeling and pharmacodynamic models. The final chapter explores Monte Carlo computing techniques for statistical inference. This book offers a systematic treatment of computer simulation in drug development. It not only deals with the principles and methods of Monte Carlo simulation, but also the applications in drug development, such as statistical trial monitoring, prescription drug marketing, and molecular docking.

This book offers a comprehensive background in community college math, which focuses on both the success and failures of past as well as cutting edge initiatives and how such initiatives can benefit students going forward. The author examines teaching strategies that have been effective throughout the history of community college math. This book will serve as a valuable resource for teachers looking to reach a diverse and heterogeneous group of students.

This book brings together a variety of probability applications through entertaining stories that will appeal to a broad readership. What are the best stopping rules for the dating problem? What can Bayes' formula tell us about the chances of a Champions League draw for soccer teams being rigged? How could syndicates win millions of lottery dollars by buying a multitude of tickets at the right time? What's the best way to manage your betting bankroll in a game in which you have an edge? How to use probability to debunk quacks and psychic mediums? How can the Monte Carlo simulation be used to solve a wide variety of probability problems? Are seven riffle shuffles of a standard deck of 52 playing cards enough for randomness? Provides seventeen engaging stories that illustrate ideas in probability. Written so as to be suitable for those with minimal mathematical background. Stories can be read independently. Can be used as examples and exercises for teaching introductory probability. These questions and many more are addressed in seventeen short chapters that can be read independently. The engaging stories are instructive and demonstrate valuable probabilistic ideas. They offer students material that they most likely don't learn in class, and offer teachers a new way of teaching their subject.

This book is the leader among the new generation of text books on quality that follow the systems approach to creating quality in products and services; the earlier generations focused solely on parts of the system such as statistical methods, process control, and management philosophy. It follows the premise that the body of knowledge and tools documented by quality professionals and researchers, when employed in designing, creating and delivering the product will lead to product quality, customer satisfaction and reduced waste. The tools employed at the different stages of the product creation cycle are covered in this book using real world examples along with their theoretical bases, strengths and weaknesses. This textbook can be used for training - from shop floor personnel to college majors in business and engineering to practicing professionals. Graduate students training as researchers in the quality field will also find useful material. The book has been used as the text for a Professional Series Massive Open Online Course offered by the Technical University of Munich on edX.org, through which tens of thousands of participants from all over the world have received training in quality methods. According to Professor Dr. Holly Ott, who chose the book for the course, the text is one of the main factors contributing to success of this MOOC. The Third Edition has been fully revised to be friendly for self-study, reflects changes in the standards referenced such as ISO 9000, and includes new examples of application of statistical tools in health care industry. Features: Reviews the history of quality movement in the U.S. and abroad Discusses Quality Cost analysis and quality's impact on a company's bottom line Explains finding customer needs and designing the product using House of Quality Covers selection of product parameters using DOE and reliability principles Includes control charts to control processes to make the product right-the-first-time Describes use of capability indices Cp and Cpk to meet customer needs Presents problem solving methodology and tools for continuous improvement Offers ISO 9000, Baldrige and Six Sigma as templates for creating a quality system

This book brings together a variety of probability applications through entertaining stories that will appeal to a broad readership. What are the best stopping rules for the dating problem? What can Bayes' formula tell us about the chances of a Champions League draw for soccer teams being rigged? How could syndicates win millions of lottery dollars by buying a multitude of tickets at the right time? What's the best way to manage your betting bankroll in a game in which you have an edge? How to use probability to debunk quacks and psychic mediums? How can the Monte Carlo simulation be used to solve a wide variety of probability problems? Are seven riffle shuffles of a standard deck of 52 playing cards enough for randomness? Provides seventeen engaging stories that illustrate ideas in probability. Written so as to be suitable for those with minimal mathematical background. Stories can be read independently. Can be used as examples and exercises for teaching introductory probability. These questions and many more are addressed in seventeen short chapters that can be read independently. The engaging stories are instructive and demonstrate valuable probabilistic ideas. They offer students material that they most likely don't learn in class, and offer teachers a new way of teaching their subject.

Big Data and Information Theory are a binding force between various areas of knowledge that allow for societal advancement. Rapid development of data analytic and information theory allows companies to store vast amounts of information about production, inventory, service, and consumer activities. More powerful CPUs and cloud computing make it possible to do complex optimization instead of using heuristic algorithms, as well as instant rather than offline decision-making. The era of "big data" challenges includes analysis, capture, curation, search, sharing, storage, transfer, visualization, and privacy violations. Big data calls for better integration of optimization, statistics, and data mining. In response to these challenges this book brings together leading researchers and engineers to exchange and share their experiences and research results about big data and information theory applications in various areas. This book covers a broad range of topics including statistics, data mining, data warehouse implementation, engineering management in large-scale infrastructure systems, data-driven sustainable supply chain network, information technology service offshoring project issues, online rumors governance, preliminary cost estimation, and information system project selection. The chapters in this book were originally published in the journal, International Journal of Management Science and Engineering Management.

Compositional Data Analysis in Practice is a user-oriented practical guide to the analysis of data with the property of a constant sum, for example percentages adding up to 100%. Compositional data can give misleading results if regular statistical methods are applied, and are best analysed by first transforming them to logarithms of ratios. This book explains how this transformation affects the analysis, results and interpretation of this very special type of data. All aspects of compositional data analysis are considered: visualization, modelling, dimension-reduction, clustering and variable selection, with many examples in the fields of food science, archaeology, sociology and biochemistry, and a final chapter containing a complete case study using fatty acid compositions in ecology. The applicability of these methods extends to other fields such as linguistics, geochemistry, marketing, economics and finance. R Software The following repository contains data files and R scripts from the book https://github.com/michaelgreenacre/CODAinPractice. The R package easyCODA, which accompanies this book, is available on CRAN -- note that you should have version 0.25 or higher. The latest version of the package will always be available on R-Forge and can be installed from R with this instruction: install.packages("easyCODA", repos="http://R-Forge.R-project.org").

This book is a timely and critical introduction for those interested in what data science is (and isn't), and how it should be applied. The language is conversational and the content is accessible for readers without a quantitative or computational background; but, at the same time, it is also a practical overview of the field for the more technical readers. The overarching goal is to demystify the field and teach the reader how to develop an analytical mindset instead of following recipes. The book takes the scientist's approach of focusing on asking the right question at every step as this is the single most important factor contributing to the success of a data science project. Upon finishing this book, the reader should be asking more questions than I have answered. This book is, therefore, a practising scientist's approach to explaining data science through questions and examples.

Key Features Collects the ideas underpinning the AHP method and discusses them together with many improvements and extensions present in the literature. As a result, the reader will receive a much more complete picture of the method. Aimed at theorists and advanced practitioners from a wide range of scientific fields, including the social, management, and technical sciences Highlights the intuitive assumptions underlying the mathematical methods that make up AHP and the pairwise comparisons method Provides software code for readers who wish to practise AHP analysis using Wolfram Language.

This is a classic book on Queues. First published in 1961 it is clearly and concisely introduces the theory of queueing systems and is still just as relevant today. The monograph is aimed at both students and operational research workers concerned with the practical investigations of queueing, although almost every statistician will find its contents of interest.

This venture aspires to be a mix of a textbook at the undergraduate and postgraduate levels and a monograph to catch the attention of researchers in theoretical and practical aspects of survey sampling at diverse levels demanding a comprehensive review of what useful materials have preceded, with an eye to what beacons to the depth of the imminent future.