A comprehensive account of the statistical theory of exponential families of stochastic processes. The book reviews the progress in the field made over the last ten years or so by the authors - two of the leading experts in the field - and several other researchers. The theory is applied to a broad spectrum of examples, covering a large number of frequently applied stochastic process models with discrete as well as continuous time. To make the reading even easier for statisticians with only a basic background in the theory of stochastic process, the first part of the book is based on classical theory of stochastic processes only, while stochastic calculus is used later. Most of the concepts and tools from stochastic calculus needed when working with inference for stochastic processes are introduced and explained without proof in an appendix. This appendix can also be used independently as an introduction to stochastic calculus for statisticians. Numerous exercises are also included.

The overall aim of the book is to introduce students to the typical course followed by a data analysis project in earth sciences. A project usually involves searching relevant literature, reviewing and ranking published books and journal articles, extracting relevant information from the literature in the form of text, data, or graphs, searching and processing the relevant original data using MATLAB, and compiling and presenting the results as posters, abstracts, and oral presentations using graphics design software. The text of this book includes numerous examples on the use of internet resources, on the visualization of data with MATLAB, and on preparing scientific presentations. As with its sister book MATLAB Recipes for Earth Sciences-3rd Edition (2010), which demonstrates the use of statistical and numerical methods on earth science data, this book uses state-of-the art software packages, including MATLAB and the Adobe Creative Suite, to process and present geoscientific information collected during the course of an earth science project. The book's supplementary electronic material (available online through the publisher's website) includes color versions of all figures, recipes with all the MATLAB commands featured in the book, the example data, exported MATLAB graphics, and screenshots of the most important steps involved in processing the graphics.

The current world financial scene indicates at an intertwined and interdependent relationship between financial market activity and economic health. This book explains how the economic messages delivered by the dynamic evolution of financial asset returns are strongly related to option prices. The Black Scholes framework is introduced and by underlining its shortcomings, an alternative approach is presented that has emerged over the past ten years of academic research, an approach that is much more grounded on a realistic statistical analysis of data rather than on ad hoc tractable continuous time option pricing models. The reader then learns what it takes to understand and implement these option pricing models based on time series analysis in a self-contained way. The discussion covers modeling choices available to the quantitative analyst, as well as the tools to decide upon a particular model based on the historical datasets of financial returns. The reader is then guided into numerical deduction of option prices from these models and illustrations with real examples are used to reflect the accuracy of the approach using datasets of options on equity indices.

Experience gained during a ten-year long involvement in modelling, program ming and application in nonlinear optimization helped me to arrive at the conclusion that in the interest of having successful applications and efficient software production, knowing the structure of the problem to be solved is in dispensable. This is the reason why I have chosen the field in question as the sphere of my research. Since in applications, mainly from among the nonconvex optimization models, the differentiable ones proved to be the most efficient in modelling, especially in solving them with computers, I started to deal with the structure of smooth optimization problems. The book, which is a result of more than a decade of research, can be equally useful for researchers and stu dents showing interest in the domain, since the elementary notions necessary for understanding the book constitute a part of the university curriculum. I in tended dealing with the key questions of optimization theory, which endeavour, obviously, cannot bear all the marks of completeness. What I consider the most crucial point is the uniform, differential geometric treatment of various questions, which provides the reader with opportunities for learning the structure in the wide range, within optimization problems. I am grateful to my family for affording me tranquil, productive circumstances. I express my gratitude to F."

Geostatistics Rio 2000 includes fifteen contributions, five of which are on applications in petroleum science and ten are on mining geostatistics. These contributions were presented at the 31st International Geological Congress, held in Rio de Janeiro, Brazil, from 6-17 August, 2000. Stochastic simulation was the key theme of these case studies. A wide range of methods was used: truncated gaussian and plurigaussian, SIS and SGS, boolean methods and multi-point attractors.

The five contributions on petroleum science focus on different aspects of reservoir characterisation. All use stochastic simulations to generate 3D numerical models that reproduce the key features of reservoirs.

Five of the ten contributions on mining present ore-body simulations; the others address questions like reconciling reserve estimates with production figures.
None of these contributions present new theory. Instead they show readers how to incorporate geology into geostatistical case studies in a meaningful way.

"Audience: " The volume will be of value to scientists, researchers, and professionals in geology, mining engineering, petroleum engineering, mathematics and statistics, as well as those working for mining and oil companies.

The series is aimed specifically at publishing peer reviewed reviews and contributions presented at workshops and conferences. Each volume is associated with a particular conference, symposium or workshop. These events cover various topics within pure and applied mathematics and provide up-to-date coverage of new developments, methods and applications.

Probabilistic expert systems are graphical networks which support the modelling of uncertainty and decisions in large complex domains, while retaining ease of calculation. Building on original research by the authors over a number of years, this book gives a thorough and rigorous mathematical treatment of the underlying ideas, structures and algorithms, emphasizing those cases in which exact answers are obtainable. It covers both the updating of probabilistic uncertainty in the light of new evidence, and statistical inference, about unknown probabilities or unknown model structure, in the light of new data. The book will be of interest to researchers and graduate students in artificial intelligence who desire an understanding of the mathematical and statistical basis of probabilistic expert systems, and to students and research workers in statistics wanting an introduction to this fascinating and rapidly developing field. The careful attention to detail will also make this work as an important reference source for all those involved in the theory and applications of probabilistic expert systems. Robert Cowell is Research Fellow and Computer Manager in the Department of Actuarial Science and Statistics of City University, London. He has been working in the field of probabilistic expert systems for over 10 years, and has published a number of research and tutorial articles in the area. A. Philip Dawid is Professor of Statistics at University College London. He has served as Editor of the Journal of the Royal Statistical Society (Series B) and Biometrika, and is currently President-Elect of the International Society for Bayesian Analysis. He holds the Guy Medal in Bronze of the Royal Statistical Society, and the G.W. Snedecor Award for the Best Publication in Biometry. He has published over 100 articles on statistics and related topics.

The present volume aims to be a comprehensive survey on the derivation of the equations of motion, both in General Relativity as well as in alternative gravity theories. The topics covered range from the description of test bodies, to self-gravitating (heavy) bodies, to current and future observations. Emphasis is put on the coverage of various approximation methods (e.g., multipolar, post-Newtonian, self-force methods) which are extensively used in the context of the relativistic problem of motion. Applications discussed in this volume range from the motion of binary systems -- and the gravitational waves emitted by such systems -- to observations of the galactic center. In particular the impact of choices at a fundamental theoretical level on the interpretation of experiments is highlighted. This book provides a broad and up-do-date status report, which will not only be of value for the experts working in this field, but also may serve as a guideline for students with background in General Relativity who like to enter this field.

Around the world a multitude of surveys are conducted every day, on a variety of subjects, and consequently surveys have become an accepted part of modern life. However, in recent years survey estimates have been increasingly affected by rising trends in nonresponse, with loss of accuracy as an undesirable result. Whilst it is possible to reduce nonresponse to some degree, it cannot be completely eliminated. Estimation techniques that account systematically for nonresponse and at the same time succeed in delivering acceptable accuracy are much needed.

"Estimation in Surveys with Nonresponse" provides an overview of these techniques, presenting the view of nonresponse as a normal (albeit undesirable) feature of a sample survey, one whose potentially harmful effects are to be minimised. Builds in the nonresponse feature of survey data collection as an integral part of the theory, both for point estimation and for variance estimation. Promotes weighting through calibration as a new and powerful technique for surveys with nonresponse. Highlights the analysis of nonresponse bias in estimates and methods to minimize this bias. Includes computational tools to help identify the best variables for calibration. Discusses the use of imputation as a complement to weighting by calibration. Contains guidelines for dealing with frame imperfections and coverage errors. Features worked examples throughout the text, using real data.

The accessible style of "Estimation in Surveys with Nonresponse" will make this an invaluable tool for survey methodologists in national statistics agencies and private survey agencies. Researchers, teachers, and students of statistics, social sciences and economicswill benefit from the clear presentation and numerous examples.

Biostatistics is the branch of statistics that deals with data relating to living organisms. This manual is a comprehensive guide to biostatistics for medical students. Beginning with an overview of bioethics in clinical research, an introduction to statistics, and discussion on research methodology, the following sections cover different statistical tests, data interpretation, probability, and other statistical concepts such as demographics and life tables. The final section explains report writing and applying for research grants and a chapter on 'measurement and error analysis' focuses on research papers and clinical trials. Key Points Comprehensive guide to biostatistics for medical students Covers research methodology, statistical tests, data interpretation, probability and more Includes other statistical concepts such as demographics and life tables Explains report writing and grant application in depth

'Et moi, ..., si j'avait su comment en revenIT, One service mathematics has rendered the je n'y serais point allt\.' human race. It has put common sense back where it belongs, on the topmost shelf next Jules Verne to the dusty canister labelled 'discarded non- The series is divergent; therefore we may be sense'. able to do something with it. Eric T. Bell O. Heaviside Mathematics is a tool for thought. A highly necessary tool in a world where both feedback and non- linearities abound. Similarly, all kinds of parts of mathematics serve as tools for other parts and for other sciences. Applying a simple rewriting rule to the quote on the right above one finds such statements as: 'One service topology has rendered mathematical physics .. :; 'One service logic has rendered com- puter science .. :; 'One service category theory has rendered mathematics .. :. All arguably true. And all statements obtainable this way form part of the raison d'etre of this series.

- The book discusses the recent techniques in NGS data analysis which is the most needed material by biologists (students and researchers) in the wake of numerous genomic projects and the trend toward genomic research. - The book includes both theory and practice for the NGS data analysis. So, readers will understand the concept and learn how to do the analysis using the most recent programs. - The steps of application workflows are written in a manner that can be followed for related projects. - Each chapter includes worked examples with real data available on the NCBI databases. Programming codes and outputs are accompanied with explanation. - The book content is suitable as teaching material for biology and bioinformatics students. Meets the requirements of a complete semester course on Sequencing Data Analysis Covers the latest applications for Next Generation Sequencing Covers data reprocessing, genome assembly, variant discovery, gene profiling, epigenetics, and metagenomics

This book contains the results of 30 years of investigation by the author into the creation of a new theory on statistical analysis of observations, based on the principle of random arrays of random vectors and matrices of increasing dimensions. It describes limit phenomena of sequences of random observations, which occupy a central place in the theory of random matrices. This is the first book to explore statistical analysis of random arrays and provides the necessary tools for such analysis. This book is a natural generalization of multidimensional statistical analysis and aims to provide its readers with new, improved estimators of this analysis.
The book consists of 14 chapters and opens with the theory of sample random matrices of fixed dimension, which allows to envelop not only the problems of multidimensional statistical analysis, but also some important problems of mechanics, physics and economics. The second chapter deals with all 50 known canonical equations of the new statistical analysis, which form the basis for finding new and improved statistical estimators. Chapters 3-5 contain detailed proof of the three main laws on the theory of sample random matrices. In chapters 6-10 detailed, strong proofs of the Circular and Elliptic Laws and their generalization are given. In chapters 11-13 the convergence rates of spectral functions are given for the practical application of new estimators and important questions on random matrix physics are considered. The final chapter contains 54 new statistical estimators, which generalize the main estimators of statistical analysis.

It is well known that the normal distribution is the most pleasant, one can even say, an exemplary object in the probability theory. It combines almost all conceivable nice properties that a distribution may ever have: symmetry, stability, indecomposability, a regular tail behavior, etc. Gaussian measures (the distributions of Gaussian random functions), as infinite-dimensional analogues of tht< classical normal distribution, go to work as such exemplary objects in the theory of Gaussian random functions. When one switches to the infinite dimension, some "one-dimensional" properties are extended almost literally, while some others should be profoundly justified, or even must be reconsidered. What is more, the infinite-dimensional situation reveals important links and structures, which either have looked trivial or have not played an independent role in the classical case. The complex of concepts and problems emerging here has become a subject of the theory of Gaussian random functions and their distributions, one of the most advanced fields of the probability science. Although the basic elements in this field were formed in the sixties-seventies, it has been still until recently when a substantial part of the corresponding material has either existed in the form of odd articles in various journals, or has served only as a background for considering some special issues in monographs.

An exploration of the use of smoothing methods in testing the fit of parametric regression models. The book reviews many of the existing methods for testing lack-of-fit and also proposes a number of new methods, addressing both applied and theoretical aspects of the model checking problems. As such, the book is of interest to practitioners of statistics and researchers investigating either lack-of-fit tests or nonparametric smoothing ideas. The first four chapters introduce the problem of estimating regression functions by nonparametric smoothers, primarily those of kernel and Fourier series type, and could be used as the foundation for a graduate level course on nonparametric function estimation. The prerequisites for a full appreciation of the book are a modest knowledge of calculus and some familiarity with the basics of mathematical statistics.

Separation of signal from noise is the most fundamental problem in data analysis, and arises in many fields, for example, signal processing, econometrics, acturial science, and geostatistics. This book introduces the local regression method in univariate and multivariate settings, and extensions to local likelihood and density estimation. Basic theoretical results and diagnostic tools such as cross validation are introduced along the way. Examples illustrate the implementation of the methods using the LOCFIT software.

This is the first book in longitudinal categorical data analysis with parametric correlation models developed based on dynamic relationships among repeated categorical responses. This book is a natural generalization of the longitudinal binary data analysis to the multinomial data setup with more than two categories. Thus, unlike the existing books on cross-sectional categorical data analysis using log linear models, this book uses multinomial probability models both in cross-sectional and longitudinal setups. A theoretical foundation is provided for the analysis of univariate multinomial responses, by developing models systematically for the cases with no covariates as well as categorical covariates, both in cross-sectional and longitudinal setups. In the longitudinal setup, both stationary and non-stationary covariates are considered. These models have also been extended to the bivariate multinomial setup along with suitable covariates. For the inferences, the book uses the generalized quasi-likelihood as well as the exact likelihood approaches.The book is technically rigorous, and, it also presents illustrations of the statistical analysis of various real life data involving univariate multinomial responses both in cross-sectional and longitudinal setups. This book is written mainly for the graduate students and researchers in statistics and social sciences, among other applied statistics research areas. However, the rest of the book, specifically the chapters from 1 to 3, may also be used for a senior undergraduate course in statistics.

Mathematical programming has know a spectacular diversification in the last few decades. This process has happened both at the level of mathematical research and at the level of the applications generated by the solution methods that were created. To write a monograph dedicated to a certain domain of mathematical programming is, under such circumstances, especially difficult. In the present monograph we opt for the domain of fractional programming. Interest of this subject was generated by the fact that various optimization problems from engineering and economics consider the minimization of a ratio between physical and/or economical functions, for example cost/time, cost/volume, cost/profit, or other quantities that measure the efficiency of a system. For example, the productivity of industrial systems, defined as the ratio between the realized services in a system within a given period of time and the utilized resources, is used as one of the best indicators of the quality of their operation. Such problems, where the objective function appears as a ratio of functions, constitute fractional programming problem. Due to its importance in modeling various decision processes in management science, operational research, and economics, and also due to its frequent appearance in other problems that are not necessarily economical, such as information theory, numerical analysis, stochastic programming, decomposition algorithms for large linear systems, etc., the fractional programming method has received particular attention in the last three decade

Statistical models and methods for lifetime and other time-to-event data are widely used in many fields, including medicine, the environmental sciences, actuarial science, engineering, economics, management, and the social sciences. For example, closely related statistical methods have been applied to the study of the incubation period of diseases such as AIDS, the remission time of cancers, life tables, the time-to-failure of engineering systems, employment duration, and the length of marriages. This volume contains a selection of papers based on the 1994 International Research Conference on Lifetime Data Models in Reliability and Survival Analysis, held at Harvard University. The conference brought together a varied group of researchers and practitioners to advance and promote statistical science in the many fields that deal with lifetime and other time-to-event-data. The volume illustrates the depth and diversity of the field. A few of the authors have published their conference presentations in the new journal Lifetime Data Analysis (Kluwer Academic Publishers).

In this volume, scientists and practitioners write about new methods and technologies for improving the operation of health care organizations. Statistical analyses play an important role in these methods with the implications of simulation and modeling applied to the future of health care. Papers are based on work presented at the Second International Conference on Health Care Systems Engineering (HCSE2015) in Lyon, France. The conference was a rare opportunity for scientists and practitioners to share work directly with each other. Each resulting paper received a double blind review. Paper topics include: hospital drug logistics, emergency care, simulation in patient care, and models for home care services.

One service mathematics has rc: ndered the 'Et moi, "', si j'avait su comment CD revenir, je n'y serais point alle. ' human race. It has put common SCIIJC back Jules Verne where it belongs. on the topmost shelf next to tbe dusty canister 1abdled 'discarded non- The series is divergent; tberefore we may be sense'. able to do sometbing witb it Eric T. Bell O. Heaviside Mathematics is a tool for thought. A highly necessary tool in a world where both feedback and non linearities abound. Similarly, all kinds of parts of mathematics serve as tools for other parts and for other sciences. Applying a simple rewriting rule to the quote on the right above one finds such statements as: 'One service topology has rendered mathematical physics . . . '; 'One service logic has rendered com puter science . . . '; 'One service category theory has rendered mathematics . . . '. All arguably true_ And all statements obtainable this way form part of the raison d'etre of this series_ This series, Mathematics and Its ApplicatiOns, started in 1977. Now that over one hundred volumes have appeared it seems opportune to reexamine its scope_ At the time I wrote "Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the 'tree' of knowledge of mathematics and related fields does not grow only by putting forth new branches."

The series is devoted to the publication of monographs and high-level textbooks in mathematics, mathematical methods and their applications. Apart from covering important areas of current interest, a major aim is to make topics of an interdisciplinary nature accessible to the non-specialist. The works in this series are addressed to advanced students and researchers in mathematics and theoretical physics. In addition, it can serve as a guide for lectures and seminars on a graduate level. The series de Gruyter Studies in Mathematics was founded ca. 35 years ago by the late Professor Heinz Bauer and Professor Peter Gabriel with the aim to establish a series of monographs and textbooks of high standard, written by scholars with an international reputation presenting current fields of research in pure and applied mathematics. While the editorial board of the Studies has changed with the years, the aspirations of the Studies are unchanged. In times of rapid growth of mathematical knowledge carefully written monographs and textbooks written by experts are needed more than ever, not least to pave the way for the next generation of mathematicians. In this sense the editorial board and the publisher of the Studies are devoted to continue the Studies as a service to the mathematical community. Please submit any book proposals to Niels Jacob. Titles in planning include Flavia Smarazzo and Alberto Tesei, Measure Theory: Radon Measures, Young Measures, and Applications to Parabolic Problems (2019) Elena Cordero and Luigi Rodino, Time-Frequency Analysis of Operators (2019) Mark M. Meerschaert, Alla Sikorskii, and Mohsen Zayernouri, Stochastic and Computational Models for Fractional Calculus, second edition (2020) Mariusz Lemanczyk, Ergodic Theory: Spectral Theory, Joinings, and Their Applications (2020) Marco Abate, Holomorphic Dynamics on Hyperbolic Complex Manifolds (2021) Miroslava Antic, Joeri Van der Veken, and Luc Vrancken, Differential Geometry of Submanifolds: Submanifolds of Almost Complex Spaces and Almost Product Spaces (2021) Kai Liu, Ilpo Laine, and Lianzhong Yang, Complex Differential-Difference Equations (2021) Rajendra Vasant Gurjar, Kayo Masuda, and Masayoshi Miyanishi, Affine Space Fibrations (2022)

Analysis of Genetic Association Studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. Students, researchers, and professionals will find the topics introduced in Analysis of Genetic Association Studies particularly relevant. The book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. In addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. Introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. The organization of this work allows for both casual reference and close study.

As a result of the COVID-19 pandemic, medical statistics and public health data have become staples of newsfeeds worldwide, with infection rates, deaths, case fatality and the mysterious R figure featuring regularly. However, we don't all have the statistical background needed to translate this information into knowledge. In this lively account, Stephen Senn explains these statistical phenomena and demonstrates how statistics is essential to making rational decisions about medical care. The second edition has been thoroughly updated to cover developments of the last two decades and includes a new chapter on medical statistical challenges of COVID-19, along with additional material on infectious disease modelling and representation of women in clinical trials. Senn entertains with anecdotes, puzzles and paradoxes, while tackling big themes including: clinical trials and the development of medicines, life tables, vaccines and their risks or lack of them, smoking and lung cancer, and even the power of prayer.

"R for Business Analytics" looks at some of the most common tasks performed by business analysts and helps the user navigate the wealth of information in R and its 4000 packages. With this information the reader can select the packages that can help process the analytical tasks with minimum effort and maximum usefulness. The use of Graphical User Interfaces (GUI) is emphasized in this book to further cut downand bend the famous learning curve in learning R. This book is aimed to help you kick-start with analytics including chapters on data visualization, code examples on web analytics and social media analytics, clustering, regression models, text mining, data mining models and forecasting. The book tries to expose the reader to a breadth of business analytics topics without burying the user in needless depth. The included references and links allow the reader to pursue business analytics topics.

This book is aimed at business analysts with basic programming skills for using R for Business Analytics. Note the scope of the book is neither statistical theory nor graduate level research for statistics, but rather it is for business analytics practitioners. Business analytics (BA) refers to the field ofexploration and investigation of data generated by businesses. Business Intelligence (BI) is the seamless dissemination of information through the organization, which primarily involves business metrics both past and current for the use of decision support in businesses. Data Mining (DM) is the process of discovering new patterns from large data using algorithms and statistical methods. To differentiate between the three, BI is mostly current reports, BA is models to predict and strategizeand DM matches patterns in big data. The R statistical software is the fastest growing analytics platform in the world, and is established in both academia and corporations for robustness, reliability and accuracy.

The book utilizes Albert Einstein s famous remarks on making things as simple as possible, but no simpler. This book will blow the last remaining doubts in your mind about using R in your business environment. Even non-technical users will enjoy the easy-to-use examples. The interviews with creators and corporate users of R make the book very readable. The author firmly believes Isaac Asimovwas a better writer in spreading science than any textbook or journal author."