Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies. Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field. The author discusses topics that include: The derivation of wave equation The mathematical solution of the wave propagation The phenomena of reflection Refraction and transmission in the acoustic field from different acoustic sources The radiation pattern of the ultrasound transducer The acoustical properties of biological tissues Ultrasound-induced bioeffects Cavitation The design of the ultrasound transducer The characterization method of the produced acoustic field An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

Sonography has emerged as a substantial diagnostic tool today. This handbook aims to cover ultrasound physics, abdominal and obstetric sonography, color Doppler, high resolution sonography and USG guided interventions with multiple choice questions and case reports for practical orientation.

Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.

The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the post-introductory chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study.

Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.

Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug's absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers. The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. In addition to describing how the analytical technologies work, the contributors explain how the data are interpreted and used in the drug registration process. A unique reference and training aid essential for every drug metabolism department or drug metabolism research team, the book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving easily across the boundaries of biology, chemistry, and physics, this is the only comprehensive, interdisciplinary resource covering the how-tos of employing radiotracers in drug development. It provides detailed information on how the science is relevant to the registration process.

The Radiologic Technology Clinical Manual is designed to guide students through all aspects of clinical training in the area of radiological sciences. This practical workbook contains student self-evaluation forms, course outlines, instructional objectives, and all the procedures and work assignments necessary for training students in the clinical side of radiologic technology. It can be used as a supplement to any radiologic sciences program. When used as part of an occupational training course in radiologic technology, the Radiologic Technology Clinical Manual will help students qualify for examination by the American Registry of Radiologic Technologists (ARRT). The book contains valuable record keeping materials for clinical experience hours, background on the profession as a whole, and evaluation forms for quarterly periods of clinical training. Time sheets, attendance forms, and clinical log forms are also included.

The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

Interaction of Radiation with Matter focuses on the physics of the interactions of ionizing radiation in living matter and the Monte Carlo simulation of radiation tracks. Clearly progressing from an elementary level to the state of the art, the text explores the classical physics of track description as well as modern aspects based on condensed matter physics. The first section of the book discusses the fundamentals of the radiation field. In the second section, the authors describe the cross sections for electrons and heavy ions-the most important information needed for simulating radiation track at the molecular level. The third section details the inelastic scattering and energy loss of charged particles in condensed media, particularly liquid water. The final section contains a large number of questions and problems to reinforce learning. Designed for radiation interaction courses, this textbook is the ideal platform for teaching students in medical/health physics and nuclear engineering. It gives students a solid grounding in the physical understanding of radiation track structure in living matter, enabling them to pursue further work in radiological physics and radiation dosimetry.

Cardiovascular Molecular Imaging is based on a groundbreaking NIH symposium sponsored by the American Society of Nuclear Cardiology. The first all-inclusive guide to the targeted molecular imaging of the cardiovascular system, it includes color illustrations throughout and is packaged with a user-friendly CD-ROM with supplemental material. This reference covers new methods for the analysis and management of cardiovascular pathophysiological processes and discusses new technologies for analyzing cardiovascular receptors, gene expression, vascular structures, and biological processes that affect the heart and associated vessels. Bridging the gap between basic science and clinical applications, the contributors: Span the most recent molecular imaging procedures used to stage disease states and assess treatment outcomes for specific cardiovascular ailments Discuss the potential of molecular imaging to provide an improved understanding of the diagnosis and management of critical cardiovascular pathophysiological processes Track the identification of targeted biological markers for molecular and physiological processes and cover their possible impact on the development of new imaging instruments and technologies Consider biochemical processes and signaling events that precede pathophysiological transformations Analyze the latest imaging technologies that enable healthcare practitioners to improve the diagnosis, treatment, and evaluation of patients with cardiovascular conditions

Offering lower toxicity and higher accuracy than conventional therapies, this source offers illustrative coverage of this new method to treat tumors associated with brain, breast, lung, and neuroendocrine cancers. Accompanied by a CD offering color images, radiolabeling procedures, and tips on radiopharmceutical administration, this source will offer comprehensive and expert guidance on this burgeoning therapeutic technique.

Explore important research approaches and concepts within diagnostic radiography Provide contemporary evidence-based practice regarding mixed method approaches Provide a clear and 'how to guide' for understanding key research principles in a wide range of radiographic settings Evaluate the impact of research on patients and the radiographer-patient relationship

First published in 1990, this indispensable volume brings together authoritative, up-to-date, critical accounts of the present status of positron emission tomography (PET) in the study of movement disorders both in terms of the basic science relevant to PET and the clinical science related to the study of specific disease processes. For better understanding, it includes a review of the basic principles of PET and tracer kinetics. It also reviews clinical studies concerning Parkinson's and Huntington's disease, as well as some of the less common movement disorders such as progressive supranuclear palsy, olivopontocerebellar atrophy, and dystonia. Throughout the text, it emphasizes PET as a tool for the quantitative measurement of meaningful biochemical and physiological processes. This state-of-the-art work provides a perspective concerning the degree to which PET studies have advanced knowledge and the future role anticipated for PET. All clinical and basic researchers interested in functional imaging with PET and movement disorders will find this book an absolute must.

New Techniques in Cardiothoracic Imaging emphasizes emerging methods in computed tomography, magnetic resonance imaging, positron-emission tomography, and similar technology. Effective use of these tools can facilitate the identification, analysis, and treatment of diseases and disorders commonly encountered in daily clinical practice. The contributors to this volume discuss: PET-CT Cardiac CT Multidetector-row helical CT High-resolution CT of the lungs Cardiac MR Functional MR Digital chest radiography Bringing readers to the forefront of the field with expert assessments of new and emerging technologies that are impacting cardiothoracic imaging, the book presents the work of seasoned experts who have developed a thorough clinical and basic knowledge in this evolving discipline and provide practical guidance on incorporating new techniques from the laboratory to the clinical practice. More than 250 highly-detailed scientific images enhance the text.

Venous Ultrasound 2e is the essential text for anyone involved in the treatment of chronic venous disease. It provides specific information on ultrasound as it is applied to chronic insufficiency, including history, general techniques, examples of anatomy, and protocols for performing ultrasound on patients, and discussions on key aspects of interpretation of sonographic findings. Updated to include the outcome and impact of three recent studies, the ATTRACT trial, the EVRA study, and the VIDIO imaging trial. An entire chapter is dedicated to iliac venous and stent imaging for those interested in expanding practice based on the mentioned studies. Also included is specific protocol for imaging of the pelvic area with focus on the pelvic congestion and reflux affecting this anatomic area. This text demonstrates that as imaging techniques improve, so too will the understanding of venous pathologies increase and the burdens of their respective pathologies. Pelvic Congestion, iliofemoral and late stage disease can be interrogated with a non-invasive approach using the techniques included prior to interventional procedures. This fully updated new edition includes coverage of new ablation techniques which include non- thermal and non- tumescent therapies for venous insufficiency - these have unique ultrasound properties on what to see, look for and observe in intra and post- operative situations. Focusing on the fundamentals that every phlebologist needs to know, the color illustrations and numerous line drawings complement the text for a complete learning experience. Key features: Covers anatomy related to venous insufficiency and obstruction Protocols with step by step approaches for those new to certain exams Includes useful diagrams and images to aid understanding Thoroughly up to date, with all the latest information for those practicing venous therapies Venous Ultrasound 2e is valuable for sonographers and physicians alike; including phlebologists, general and vascular surgeons, physicians, radiologists, angiologists, interventional cardiologist, mid-levels, and nurses who work in this area.

This book contains a series of clinical cases that address and illustrate difficult problems in obstetric ultrasound. The approach is strongly didactic and will aid trainees in maternal-fetal medicine and obstetrics to appreciate potential pitfalls and recognize rare presentations. Each case sets out one page of text, then one of treatment algorithms, and then presents sample ultrasound scans. Learning objectives are given for each case, together with a short list of references and background reading.

With 2300 radiological images dispersed throughout the text, this source provides an expansive armamentarium of case studies and examples showcasing both common and uncommon liver pathologies. Serving as an unparalleled how-to source for the investigation of liver disease by MRI, this guide demonstrates key MRI techniques currently utilized in clinical practice, as well as explains the choice of acquisition sequences, specific parameters, and the use of contrast media for each application.

The only book available on transesophageal echocardiography of the mitral valve, this impressive and highly illustrated text provides a concise yet in-depth analysis of the mitral valve from an experience of over 10,000 transesophageal echocardiograms performed by the authors. A starting point or 'how-to' reference for studying the mitral valve with transesophageal echocardiography, Mitral Valve Transesophageal Echocardiography is also a highly useful resource for diagnostic examples of mitral pathology for physicians who practice transesophageal echocardiography.

The first MATLAB (R) programming book written specifically for clinical radiotherapy medical physicists and medical physics trainees, this much-needed book teaches users how to create their own clinical applications using MATLAB (R), as a complement to commercial software particularly when the latter does not cover specific local clinical needs. Chapters explore key radiotherapy areas such as handling volumes, 3D dose calculation, comparing dose distributions, reconstructing treatment plans and their summations, and automated tests for machine quality assurance. Readers will learn to independently analyse and process images, doses, structures, and other radiotherapy clinical data to deal with standard and non-standard situations in radiotherapy. This book will also significantly improve understanding of areas such as data nature, information content, DICOM RT standard, and data flow. It will be an invaluable reference for students of medical physics, in addition to clinical radiotherapy physicists and researchers working in radiotherapy. Features: Includes real clinical medical physics applications derived from actual clinical problems Provides commented MATLAB (R) scripts working with sample data and/or own data matching input requirements Promotes critical thinking and practical problem solving skills

Brachytherapy is continuously advancing. Years of accumulated experience have led to clinical evidence of its benefit in numerous clinical sites such as gynecological, prostate, breast, rectum, ocular, and many other cancers. Brachytherapy continues to expand in its scope of practice and complexity, driven by strong academic and commercial research, by advances in competing modalities, and due to the diversity in the political and economic landscape. It is a true challenge for practicing professionals and students to readily grasp the overarching trends of the field, especially of those technologies and innovative practices that are not yet established but are certainly on the rise. Addressing this challenge, Emerging Technologies in Brachytherapy presents a comprehensive collection of chapters on the latest trending/emerging technologies and expert opinions. It is divided into five broad sections: Section I: Physics of Brachytherapy Section II: Imaging for Brachytherapy Guidance Section III: Brachytherapy Suites Section IV: Is Brachytherapy a Competitive Modality? Section V: Vision 20/20: Industry Perspective Each section has a carefully selected collection of chapters, which covers the spectrum of topics in comprehensive detail. By drawing on recognized experts and key opinion leaders from academia and commercial sectors worldwide (100+ contributors), Emerging Technologies in Brachytherapy provides readers with a wealth of relevant information needed to comprehend the rapidly advancing technologies and trends of today and the prospects for the future.

This book illustrates 100 classic radiologic signs with radiograms alongside illustrative photographs for memory aids and clarification. Accompanying text explains the history and meaning of the descriptive name. The entry for "dromedary hump," for example, shows a typical x-ray of this condition with a photograph of a dromedary camel that clearly shows how the name fits the sign. Dr. Mulligan says, "In honor of the 100th anniversary of Roentgen's discovery, this book illustrates and elaborates on the history of 100 of the more classic radiologic signs. If we are to use these terms with full understanding, we must have the ability to visualize the object depicted by the term, imagine its radiographic appearance, and transfer that picture to the radiographic image before us. This book is intended to help practitioners and students of our art accomplish that task."

Gain mastery over the fundamentals of radiation oncology physics! This package gives you over 60 tutorial videos (each 15-20 minutes in length) with a companion text, providing the most complete and effective introduction available. Dr. Ford has tested this approach in formal instruction for years with outstanding results. The text includes extensive problem sets for each chapter. The videos include embedded quizzes and "whiteboard" screen technology to facilitate comprehension. Together, this provides a valuable learning tool both for training purposes and as a refresher for those in practice. Key Features A complete learning package for radiation oncology physics, including a full series of video tutorials with an associated textbook companion website Clearly drawn, simple illustrations throughout the videos and text Embedded quiz feature in the video tutorials for testing comprehension while viewing Each chapter includes problem sets (solutions available to educators)

Updated to reflect the latest scientific advances and technologies in the diagnosis and treatment of pleural diseases, this new Second Edition explores the structure and function of these diseases and malignancies, from tuberculosis and asbestos to pleurisy and pneumothorax. Edited by leading international authorities in pulmonary medicine, this comprehensive guide is an invaluable resource for pulmonologists, radiologists, and critical care physicians. Pleural Disease, Second Edition highlights: molecular and diagnostic approaches interventional applications, including pleural thoracentesis and closed biopsy, chest tube insertion, pleural lavage, medical thoracoscopy, and VATS biomarkers and proteomics translational medicine approaches, new treatment methodologies, and clinical manifestations various diagnostic tests and the importance of clinical evaluation in the differential diagnosis of a pleural effusion new surgical and non-surgical techniques to identify and diagnose pleural diseases, including: medical thoracoscopy, pleural lavage, intrapleural fibrinolytics, image-guided small bore catheters, video-assisted thoracoscopic surgery (VATS), pleuroperitoneal shunt, and extrapleural pneumonectomy

Voracious Children explores food and the way it is used to seduce, to pleasure, and coerce not only the characters within children's literature but also its readers. There are a number of gripping questions concerning the quantity and quality of the food featured in children's fiction that immediately arise: why are feasting fantasies so prevalent, especially in the British classics? What exactly is their appeal to historical and contemporary readers? What do literary food events do to readers? Is food the sex of children's literature? The subject of children eating is compelling but, why is it that stories about children being eaten are not only horrifying but also so incredibly alluring? This book reveals that food in fiction does far, far more that just create verisimilitude or merely address greedy readers' desires. The author argues that the food trope in children's literature actually teaches children how to be human through the imperative to eat "good" food in a "proper" controlled manner. Examining timely topics such as childhood obesity and anorexia, the author demonstrates how children's literature routinely attempts to regulate childhood eating practices and only award subjectivity and agency to those characters who demonstrate "normal" appetites.
Examining a wide range of children's literature classics from Little Red Riding Hood to The Lion, the Witch and the Wardrobe, this book is an outstanding and unique enquiry into the function of food in children's literature, and it will make a significant contribution to the fields of both children's literature and the growing interdisciplinary domain of food, culture and society.

To succeed in radiology, you not only need to be able to interpret diagnostic images accurately and efficiently; you also need to make wise decisions about managing your practice at every level. Whether you work in a private, group, hospital, and/or university setting, this practical resource delivers the real-world advice you need to effectively navigate day-to-day financial decisions, equipment and computer systems choices, and interactions with your partners and staff. Equips you to make the best possible decisions on assessing your equipment needs * dealing with manufacturers * purchasing versus leasing * and anticipating maintenance costs and depreciation. Helps you to identify your most appropriate options for picture archiving systems and radiology information systems * security issues * high-speed lines * storage issues * workstation assessments * and paperless filmless flow. Offers advice on dealing with departments/clinicians who wish to perform radiological procedures and provides strategies for win-win compromises, drawing the line, inpatient-versus-outpatient considerations, cost and revenue sharing, and more.

This book provides simple and practical instructions on how to perform safe and easy venous cannulation, and how to insert midlines and PICC lines using ultrasound. It aidsunderstanding of the relevant anatomy, shows how to use the ultrasound machine, and how to insert such lines using ultrasound guidance. Readers will feel confident and well prepared to deal with patients requiring difficult venous access, giving them simple solutions that can be learned very quickly. These skills will also be globally beneficial for patients and healthcare institutions alike. Follows the trends of the NHS and riding the wave of the midline/PICC line revolution Compact and affordable highly relevant to daily practice Useful for specialists and generalists alike, truly multi-disciplinary