This volume contains information on the diagnosis, therapy, and prognosis of spinal tumors. Various aspects of different major types of spinal tumors (astrocytomas, ependymomas, and oligodendroglioma) are discussed. Insights into the understanding of molecular pathways involved in tumor biology are explained. Classification of intradural spinal tumors, including the percentages of each of the three major types, is detailed. Symptoms, radiological features, and clinicopathological parameters of spinal cord tumors are explained. Diagnosis, outcome, and prognosis of primary spinal cord and oligodendroglioma are discussed. Diagnosis of some other spinal tumors (e.g., pilomyxoid and chordomas) is also explained. The useful role of neuroimaging in diagnosing spinal teratoid/rhabdoid and gangliogliomas is included. A wide variety of treatments of a number of spinal cord tumor types are presented in detail. Therapies discussed include chemotherapy, surgery, radiosurgery, stereotactic radiosurgery, Cyberknife stereotactic radiotherapy, standard radiation alone, and rhenium-186 intracavity radiation. Also are duiscussed embolozation and spondylectomy. The usefulness of transplantation of human embryonic stem cells-derived oligodendrocyte progenitors and motoneuron progenitors in the repair of injured spinal cord is emphasized. Symptoms of the advent of spinal tumors are pointed out. Introduction to new technologies and their applications to spinal cord tumor diagnosis, treatment, and therapy assessment are explained.

Intended for practising rheumatologists, this book will also be useful for postgraduate students and internists with an interest in rheumatology. It familiarises clinicians involved in the care of patients with spondyloarthritis (SpA) with various common and uncommon imaging features of these disorders. In addition, it will serve as a reference for comparison of imaging features observed by clinicians in their day-to-day practice. The purpose is to make it easier for a rheumatologist to understand the report given by a radiologist in this context and to participate with a basic understanding during multidisciplinary meetings involving radiology colleagues. The aim is to ensure better patient care through shared understanding of imaging findings. Detailed illustrations and explanation of various imaging findings in patients with spondyloarthritis. Basic science of MRI and its sequences have been explained in a simple language which rheumatologists and internists can understand. Various uncommon imaging features like entheseal inflammation and ligamentous ossification have been nicely illustrated. Provides a vivid collection of plain radiographs, MRIs and CT scans obtained during care of patients with spondyloarthritis. Both the axial and peripheral joints have been included.

This book provides useful information on conventional radiology which will help the pediatricians in their day-to-day office practice as a ready to refer guide in pediatric radiological investigations. Discusses the discovery and evolution of X-rays. Provides an outline of radiation hazards, types of X-rays and radiographic positions in pediatrics. Advent of Digital Radiography and case scenarios of clinical importance added in all essential chapters. Contains information on emergency radiological investigation. This book will be of immense help for UG and PG students, practicing pediatricians and teaching faculties alike.

The new edition of the book Normal and Abnormal Swallowing, Second Edition, presents an updated practical approach to the role of imaging in the diagnosis and treatment of the patient with dysphagia. Centered around the "gold standard" imaging modality, i.e. videofluorography, the text also includes chapters on other modalities such as ultrasound, computed tomography and magnetic resonance imaging. The broad scope of the text makes it the definitive reference work for professionals already involved with patients with dysphagia as well as newcomers interested in learning more about the imaging approaches to these patients. This is a "must read" for professionals in specialities such as radiology, gastroenterology, otolaryngology, rehabilitation medicine and speech language pathology.

This detailed volume will focus on the phenomenon of RNA interference by providing comprehensive coverage of various techniques for in vivo micro/siRNA imaging including the design and synthesis of specific imaging agents and tools, the development of imaging methodologies, and their interpretation. An essential element in the development and optimization of these therapies is the ability to measure the bioavailability and functionality of the RNA/oligonucleotide molecule after administration into the body. Noninvasive imaging provides the necessary set of tools to accomplish this in authentic physiologic environments and across time. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Imaging: Methods and Protocols serves physicians, scientists, and graduate students who are either new to the field of RNA-based imaging and its associated therapeutic applications or who wish to be apprised of recent advances in the state of the art.

Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.

This book is a comprehensive guide to imaging techniques for the diagnosis and management of genitourinary disorders. Divided into five key sections, the text covers diagnostic imaging of the urinary tract and the genital tract in both men and women. This fourth edition has been fully revised to provide clinicians with the latest advances and techniques in the field. New chapters on radiological anatomy and novel imaging techniques have been included. Latest guidelines and systematic-algorithms are covered to assist understanding and simplify diagnostic reporting. Radiological images, diagrams and figures further enhance the thorough text. Key points Comprehensive guide to diagnostic imaging techniques for genitourinary diseases and disorders Fully revised, fourth edition detailing latest advances in the field Includes new chapters on radiological anatomy and novel imaging techniques Previous edition (9788184486827) published in 2009

This book covers emerging trends in signal processing research and biomedical engineering, exploring the ways in which signal processing plays a vital role in applications ranging from medical electronics to data mining of electronic medical records. Topics covered include statistical modeling of electroencephalograph data for predicting or detecting seizure, stroke, or Parkinson's; machine learning methods and their application to biomedical problems, which is often poorly understood, even within the scientific community; signal analysis; medical imaging; and machine learning, data mining, and classification. The book features tutorials and examples of successful applications that will appeal to a wide range of professionals and researchers interested in applications of signal processing, medicine, and biology.

A practical, highly useful guide to the principles of I.C.U. chest radiology, complete with case studies and radiographs on CD For critically ill patients in a hospital's I.C.U., a portable chest radiograph is the most helpful, and most commonly used, x-ray examination. Cardiopulmonary complications and the malposition of lines, tubes, and catheters are often initially detected on a portable chest film. It is essential for hospital personnel to know how to approach and read these films, and yet little attention has been paid to teaching the accurate evaluation of this crucial diagnostic tool. The first book in more than a decade to specifically address this topic, I.C.U. Chest Radiology is an authoritative and concise guide to interpreting portable chest film; identifying and correcting any abnormal positions in the various devices inserted into the vascular and respiratory systems; and diagnosing abnormalities of the cardiopulmonary system. Radiology expert Dr. Harold Moskowitz outlines his approach and philosophy toward x-ray interpretation of the I.C.U. patient one that can be used daily and in any I.C.U. setting. Divided into ten straightforward chapters, the book begins with a discussion of the physics necessary to obtain a proper film and moves on to the more clinical problems encountered each day in the I.C.U. such as airspace disease, barotrauma, pneumonia, congestive failure, and malalignment of tubes and lines. Throughout, Moskowitz points out specific findings that can often make a difference in a patient's management. Supporting these detailed chapters is a CD featuring real-life case studies and radiographic images that simulate common problems in the I.C.U. This is a unique way for readers to prepare to handle the all-too-common scenario: the 2:00 a.m. call from an I.C.U. nurse that a patient has "crashed" and needs attention. Using knowledge gleaned from the chapters, the reader is encouraged to study the radiogra

Developments in teleradiology are progressing at great speed. As a consequence, there is a need for a broad overview of the field. This first-ever book on teleradiology is presented in such a way that it should make it accessible to anyone, independent of their knowledge of technology. The text is designed to be used by all professionals, including radiologists, surgeons, nurses and allied health professionals, and computer scientists. In a very short time, driven by technical developments, the field of teleradiology has become too extensive to be covered by only a small number of experts. Therefore, Teleradiology has been written with chapter contributions from a host of renowned international authorities in teleradiology (see the Contents and the Contributors). This ensures that the subject matter focusing on recent advances in teleradiology is truly up to date. Our guiding hope during this task was that as editors of multiple chapters we could still write with a single voice and keep the content coherent and simple. We hope that the clarity of this book makes up for any limitations in its comp- hensiveness.

An in-depth introduction to radiotherapy physics emphasizing the clinical aspects of the field. This second edition gradually and sequentially develops each of its topics in clear and concise language. It includes important mathematical analyses, yet is written so that these sections can be skipped, if desired, without compromising understanding. The book consists of seven parts covering basic physics (Parts I-II), equipment for radiotherapy (Part III), radiation dosimetry (Parts IV-V), radiation treatment planning (Part VI), and radiation safety and shielding (Part VII). An invaluable text for radiation oncologists, radiation therapists, and clinical physicists.

Based on the author's lecture notes and research, this well-illustrated and comprehensive text is one of the first to provide an introduction to image registration with particular emphasis on numerical methods in medical imaging. Ideal for researchers in industry and academia, it is also a suitable study guide for graduate mathematicians, computer scientists, engineers, medical physicists, and radiologists. Image registration is utilised whenever information obtained from different viewpoints needs to be combined or compared and unwanted distortion needs to be eliminated. For example, CCTV images, ultrasound images, brain scan images, fingerprint and retinal scanning. Modersitzki's book provides a systematic introduction to the theoretical, practical, and numerical aspects of image registration, with special emphasis on medical applications. Various techniques are described, discussed and compared using numerous illustrations. The text starts with an introduction to the mathematical principles and the motivating example of the Human Neuroscanning Project whose aim is to build an atlas of the human brain through reconstructing essential information out of deformed images of sections of a prepared brain. The introduction is followed by coverage of parametric image registrations such as landmark based, principal axes based, and optimal affine linear registration. Basic distance measures like sum of squared differences, correlation, and mutual information are also discussed. The next section is devoted to state-of-the-art non-parametric image registrations where general variational based framework for image registration is presented and used to describe and compare well-known and new image registration techniques. Finally, efficient numerical schemes for the underlying partial differential equations are presented and discussed. This text treats the basic mathematical principles, including aspects from approximation theory, image processing, numerics, partial differential equations, and statistics, with a strong focus on numerical methods in image processing. Providing a systematic and general framework for image registration, the book not only presents state-of-the-art concepts but also summarises and classifies the numerous techniques to be found in the literature.

This book is a comprehensive review of a myriad of cases, a practical board review, a resource for maintenance of certification, and an interesting read with relevant images. The cases are real-life examples seen by radiologists around the United States. It is beneficial to the practicing radiologists, residents and fellows. A comprehensive ultrasound review book in a case-based format. Contains 125 cases to give a practical review. Each case includes a thorough discussion of ultrasound findings, many including cross-sectional correlation. Differential diagnoses are presented along with diagnostic pearls and management options.

This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.

Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.

Senior scientists from neighboring and other NATO countries joined their efforts to help this region to get to know their problems, discussed their solutions and how they can be helped out. Distinguished experts described how they had succeeded in developing the solutions to such problem in their countries.

Dr. William Herring's Learning Radiology: Recognizing the Basics, 5th Edition, remains the leading introductory radiology text for medical students and others who are required to read and interpret common radiologic images. Using an easy-to-follow pattern recognition approach, this clearly written, highly illustrated text teaches how to differentiate normal and abnormal images of all modalities. From the basics of patient safety, dose reduction, and radiation protection to the latest information on ultrasound, MRI, and CT, it provides a complete, up-to-date introduction to radiology needed by today's students. Uses a clear, conversational writing style-with a touch of humor-to explain what you need to know to effectively interpret medical images of all modalities. Teaches how to arrive at a diagnosis by following a pattern recognition approach, and logically overcome difficult diagnostic challenges with the aid of decision trees. Employs an easy-to-read, bullet-point format, including bolded key points and icons designating special content: Diagnostic Pitfalls, Really Important Points, Take-Home Points, and Weblinks. Features more than 850 high-quality illustrations, useful tables, case study questions, and teaching boxes throughout. Shares the extensive knowledge and experience of esteemed author Dr. William Herring, a skilled radiology teacher and the host of his own specialty website, www.learningradiology.com. Offers quick review and instruction for medical students, residents, and fellows, as well as those in related fields such as nurse practitioners and physician assistants. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud-as well as access bonus content, including new appendices covering the Discovery of X-rays, Diagnostic Radiology Signs, and Artificial Intelligence in Radiology; USMLE-style Q 30 videos; and more.

Reflecting the expanding field's need for reliable protocols, Fluorescence Spectroscopy and Microscopy: Methods and Protocols offers techniques from a worldwide team of experts on this versatile and vital subject. The topics covered fall into four broad categories: steady-state fluorescence spectroscopy, time-resolved fluorescence spectroscopy, fluorescent probe development, and the various sub-categories of fluorescence microscopy, such as fluorescence recovery after photobleaching (FRAP), live cell FRET imaging (FRETim), fluorescence lifetime imaging (FLIM), fluorescence fluctuation spectroscopy (FFS), and single-molecule fluorescence spectroscopy (smFS). Written as a part of the popular Methods in Molecular Biology series, chapters include the kind of unambiguous detail and key implementation advice that proves essential for successful results. Comprehensive and practical, Fluorescence Spectroscopy and Microscopy: Methods and Protocols aims to guide both 'novice' and established scientists toward furthering their research with these invaluable techniques.

This is the third volume in the series, in which the topic of the effects of radio frequencies on human tissue, now increasingly a concern with the prevalence of cell phones, is explored by Prof. Lin and other researchers. The impact of electromagnetics on imaging and cardiology, both very keen areas of research at present, is also explored.

This book presents important recent developments in mathematical and computational methods used in impedance imaging and the theory of composite materials. By augmenting the theory with interesting practical examples and numerical illustrations, the exposition brings simplicity to the advanced material. An introductory chapter covers the necessary basics. An extensive bibliography and open problems at the end of each chapter enhance the text.

Provides concise, handy and clear reference and in-depth knowledge of various ultrasound images in relation to various disease entities of different systems of the body so as to arrive at a correct diagnosis. Serves as an essential guide to practicing radiologists, sonologists, obstetricians and gynaecologists, physicians and surgeons and also to postgraduate students in their examination.

This thesis offers an accessible guide to biomedical phase-contrast imaging with over 20 radiographic illustrations. It focuses on research to improve radiography, and particularly mammography applications, by using a novel X-ray imaging modality that exploits the wave-nature of X-rays, rather than just their absorption in tissue. Further, it explores a broad range of potential applications - from the assessment of breast cancer and the evaluation of microcalcification clusters, to the examination of renal stones. X-ray imaging is an indispensable tool in modern medical diagnostics, and ranges from simple radiography applications to advanced CT imaging protocols. This novel phase-contrast approach has the potential to deliver significantly improved diagnostic information, also and especially in cases where mammography is used for screening purposes. The thesis is based on several studies conducted by the author - working in close interdisciplinary cooperation with medical doctors at two university clinics in Munich - and successfully demonstrates this diagnostic potential in pre-clinical experiments.

This textbook presents in a unified manner the fundamentals of both continuous and discrete versions of the Fourier and Laplace transforms. These transforms play an important role in the analysis of all kinds of physical phenomena. As a link between the various applications of these transforms the authors use the theory of signals and systems, as well as the theory of ordinary and partial differential equations. The book is divided into four major parts: periodic functions and Fourier series, non-periodic functions and the Fourier integral, switched-on signals and the Laplace transform, and finally the discrete versions of these transforms, in particular the Discrete Fourier Transform together with its fast implementation, and the z-transform. This textbook is designed for self-study. It includes many worked examples, together with more than 120 exercises, and will be of great value to undergraduates and graduate students in applied mathematics, electrical engineering, physics and computer science.

This book provides a review of imaging techniques and applications in stem cell transplantation and other cell-based therapies. The basis of different molecular imaging techniques is explained in detail, as is the current state of interventional radiology techniques. While the whole is a comprehensive discussion, each chapter is self-sufficient enough so that each can be reviewed independently. The contributors represent years of international and cross-disciplinary expertise and perspective and are all well known in their fields. comprehensive information on the role of clinical and molecular imaging in stem cell therapy from this book reviewed in detail. Essential reading for radiologists and physicians who are interested in developing a basic understanding of stem cell imaging and applications of stem cells and cell based therapies. However, it will also be of interest to clinical scientists and researchers alike, including those involved in stem cell labeling, tracking & imaging, cancer therapy, angiogenesis and cardiac regeneration.

This book presents the latest research findings and reviews in the field of medical imaging technology, covering ultrasound diagnostics approaches for detecting osteoarthritis, breast carcinoma and cardiovascular conditions, image guided biopsy and segmentation techniques for detecting lung cancer, image fusion, and simulating fluid flows for cardiovascular applications. It offers a useful guide for students, lecturers and professional researchers in the fields of biomedical engineering and image processing.