"Mechanobiology of Cell-Matrix Interactions" focuses on
characterization and modeling of interactions between cells and
their local extracellular environment, exploring how these
interactions may mediate cell behavior. Studies of cell-matrix
interactions rely on integrating engineering, (molecular and
cellular) biology, and imaging disciplines. Recent advances in the
field have begun to unravel our understanding of how cells gather
information from their surrounding environment, and how they
interrogate such information during the cell fate decision making
process. Topics include adhesive and integrin-ligand interactions;
extracellular influences on cell biology and behavior; cooperative
mechanisms of cell-cell and cell-matrix interactions; the
mechanobiology of pathological processes; (multi-scale) modeling
approaches to describe the complexity or cell-matrix interactions;
and quantitative methods required for such experimental and
modeling studies.
General
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