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Proteogenomics (Hardcover, 1st ed. 2016)
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Proteogenomics (Hardcover, 1st ed. 2016)
Series: Advances in Experimental Medicine and Biology, 926
Expected to ship within 12 - 17 working days
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This book highlights key technologies and identifies areas for
further development in proteogenomics. The utility and usefulness
of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq,
ribosome profiling, mass spectrometry- and antibody-based
proteomics) is discussed and opportunities and challenges of
related bioinformatics applications are outlined. The reader will
be able to appreciate the interdisciplinary nature of the
continuously evolving area of proteogenomics, which has already
grown beyond its original concept of verifying gene annotations by
proteomics. The chapters presented in this book are arranged to
offer a general overview, rather than to provide detailed
descriptions of technologies. The selected applications will
provide useful insight into the level of detail that can be
obtained in relation to certain diseases areas, including cancer
biology and personalized medicine. The readers will find that each
chapter delivers a comprehensive approach to proteogenomics, each
from the point of view of a specific application. Research
scientists interested in innovative processes that can offer a
unique and at the same time a more complete access to technological
developments and concepts that in turn can contribute to a better
understand biological functions should read this book.
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