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Antimicrobial Resistance in Developing Countries (Paperback, 2010 ed.)
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Antimicrobial Resistance in Developing Countries (Paperback, 2010 ed.)
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Avoiding infection has always been expensive. Some human
populations escaped tropical infections by migrating into cold
climates but then had to procure fuel, warm clothing, durable
housing, and crops from a short growing season. Waterborne
infections were averted by owning your own well or supporting a
community reservoir. Everyone got vaccines in rich countries, while
people in others got them later if at all. Antimicrobial agents
seemed at first to be an exception. They did not need to be
delivered through a cold chain and to everyone, as vaccines did.
They had to be given only to infected patients and often then as
relatively cheap injectables or pills off a shelf for only a few
days to get astonishing cures. Antimicrobials not only were better
than most other innovations but also reached more of the world's
people sooner. The problem appeared later. After each new
antimicrobial became widely used, genes expressing resistance to it
began to emerge and spread through bacterial populations. Patients
infected with bacteria expressing such resistance genes then failed
treatment and remained infected or died. Growing resistance to
antimicrobial agents began to take away more and more of the cures
that the agents had brought.
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