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Gaucher Disease (Hardcover)
Loot Price: R7,830
Discovery Miles 78 300
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Gaucher Disease (Hardcover)
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In September of 2007 Gaucher Disease received a commendation in the
Haematology category of the 2007 British Medical Association
Medical Book Competition! Although rare in the general population,
Gaucher disease is the most prevalent of the lysosomal storage
disorders, making research into this particular orphan disorder an
invaluable prototype for the diagnosis, research, and treatment of
others. Like many rare conditions, Gaucher disease has benefited
from the explosion of medical research in the last decade, the
amount of new information on this disease is staggering and the
rate of new discoveries has left previous books on the subject
unable to provide useful, up-to-date information. The most current,
fully comprehensive reference to date, Gaucher Disease provides
valuable information for academic and industry scientists, and
clinicians. Outlining the latest research on the biochemical
mechanisms and pathology of lysosomal storage disorders, this book
covers diverse topics including animal models, crystallography,
imaging and radionuclide evaluation. It not only addresses the
developmental basis for current treatments like the now widely
available enzyme replacement therapy, but also includes chapters
introducing new therapies on the horizon. With contributions from
world-renowned experts in substrate reduction therapy,
pharmaceutical chaperone therapy, hematopoietic stem cell
transplantation and gene therapy, as well as chapters on a second
generation of enzyme replacement therapy, this book explores the
full spectrum of possibilities offered by the most recent advances
in medicine. Some of the most interesting aspects of the book
include the discussions on patient management, those touching on
the ethics of research, and the societal aspects of treating rare
diseases with expensive therapy.
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