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Genomic Diversity in People of India - Focus on mtDNA and Y-Chromosome polymorphism (Paperback, 1st ed. 2021)
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Genomic Diversity in People of India - Focus on mtDNA and Y-Chromosome polymorphism (Paperback, 1st ed. 2021)
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This book is the output of Anthropological Survey of India's
National Project "DNA Polymorphism of Contemporary Indian
Population" conducted during 2000 to 2018. The book compiles the
independent and collaborative work of 49 scientific personnel.
Genomics facilitate the study of genetic constitution and diversity
at individual and population levels. Genomic diversity explains
susceptibility, predisposition and prolongation of diseases;
personalized medicine and longevity; prehistoric demographic
events, such as population bottleneck, expansion, admixture and
natural selection. This book highlights the heterogeneous,
genetically diverse population of India. It shows how the central
geographic location of India, played a crucial role in historic and
pre-historic human migrations, and in peopling different continents
of the world. The book describes the massive task undertaken by
AnSI to unearth genomic diversity of India populations, with the
use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y
-chromosome in 75 communities. The book talks about the 61 maternal
and 35 paternal lineages identified through these studies. It
brings forth interesting, hitherto unknown findings such as shared
mutations between certain communities. This volume is a milestone
in scientific research to understand biological diversity of Indian
people at genomic level. It addresses the basic priority to
identify different genes underlying various inborn genetic defects
and diseases specific to Indian populations. This would be highly
interesting to population geneticists, historians, as well as
anthropologists.
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