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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Complement Regulatory Proteins (Hardcover)
Loot Price: R3,089
Discovery Miles 30 890
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Complement Regulatory Proteins (Hardcover)
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From small beginnings in the early 1970s, the study of complement
regulatory proteins has grown in the last decade to the point where
it dominates the complement field. This growth has been fueled by
the discovery of new regulators, the cloning of old and new
regulators, the discovery that many of the regulators are
structurally and evolutionarily related to each other and the
development of recombinant forms for use in therapy. There are now
more proteins known to be involved in controlling the complement
system than there are components of the system and the list
continues to grow. The time is ripe for a comprehensive review of
our current knowledge of these intriguing proteins. This book does
just that. The first few chapters discuss the "nuts-and-bolts" of
the complement regulators, describing their structures, functional
roles and modes of action. The roles of the complement regulators
"in vivo" are then described, focusing on the consequences of
deficiency, roles in the reproductive system, interactions with
pathogens and exploitation for therapy. The interesting
developments in defining the complement regulators expressed in
other species are also discussed. The book is written as a
monograph, albeit by two people. The text is as readable as
possible without compromising on scientific accuracy and
completeness. The conversational style very evident in some
sections is deliberate Placing all references in a single
bibliography at the end of the text further improves readability.
The reader will go to the book to discover a specific fact but be
persuaded to read more and derive pleasure from the process. The
authors' enthusiasm for the subject comes over strongly in the
text, and this enthusiasm proves infectious.
Key Features
* Complement regulators--structure, functional roles and mode of
action
* Comprehensive reviews of each of the individual regulators
* Roles of Complement regulators "in vivo, "in health and disease:
* Consequences of deficiency
* Roles in the reproductive system
* Interactions with pathogens
* Exploitation for therapy
* Complement regulators in other species
General
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