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The HLA System in Clinical Transplantation - Basic Concepts and Importance (Paperback, Softcover reprint of the original 1st ed. 1993)
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The HLA System in Clinical Transplantation - Basic Concepts and Importance (Paperback, Softcover reprint of the original 1st ed. 1993)
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With this book we* want to address young graduate students, clini
cians involved in transplantation, and technicians in
transplantation immunology laboratories. The volume should give a
comprehensive but basic, up to date introduction to the structure,
function, and clinical importance of the HLA system. We believe
that there is a need for such a survey, and think that the present
level of our knowledge is an optimal occasion for publication. A
significant number of ques tions have now been resolved, and our
knowledge has reached a level of sophistication that provides the
basis for additional questions and answers. Although the emphasis
of this book is on the role of HLA anti gens in clinical
transplantation, their involvement in other clinical contexts is
also discussed. The main focus is on the human MHC an tigenic
system, but MHC systems in other species are described as they
contribute to our understanding of the structural and functional
characteristics of HLA antigens. Some important issues related to
laboratory techniques are also covered. The contributors have a
close affiliation to the field of transplan tation immunology. A
majority have even been playing important roles in unraveling the
HLA system and its functions. We believe this has contributed
significantly to the quality and clinical and practical relevance
of the book. As editors, we drew up the principal guidelines and
took care that the chapters can be read as separate entities,
although this invariably results in some overlapping.
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