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New Trends in Corynebacterium Glutamicum - Beyond the Amino Acids (Hardcover)
Loot Price: R5,839
Discovery Miles 58 390
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New Trends in Corynebacterium Glutamicum - Beyond the Amino Acids (Hardcover)
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Over fifty years of scientific and industrial developments focused
on the amino acid producer bacterium Corynebacterium glutamicum has
successfully yielded up to 2.93 and 1.95 million tons/year of L
glutamic acid and L-lysine, respectively. As a result of this
biotechnological effort, a massive amount of knowledge decidedly
applicable to the development of new products has been gained.
Nowadays, this knowledge is used to enlarge the portfolio of C.
glutamicum industrial products, since they are highly relevant as
chemicals, biodegradable polymers, ingredients, or additives in
food, feed, cosmetics and pharmaceuticals. This book addresses
production of these new metabolites (C. glutamicum applications)
and their potential under the expert point of view of those groups
directly involved in their developments. Thus, amino acids out of
the traditional glutamic acid or lysine, as L valine; food
colorants such as carotenoids; dicarboxylic acids used as building
blocks (e.g: succinate); alpha hydroxy acids as L lactate, D
lactate or glycolate; biodegradable polyester (eg.:
polyhydroxybutyrate); alcohols for biofuel as isobutanol as well as
bioremediation applications of the new developments around C.
glutamicum described in this book. Those industrial relevant
compounds come to the market parallel with the developing
application of new technologies. Hence, cell activity as a whole by
means of the Proteomics or Transcriptomics approaches, as well as
the methodologies that mimic the large fermetor conditions in a
scale-down format are also reviewed in the book. Additionally, a
historical description and an updated review of the taxonomical
environment of Corynebacterium genus open an essential manual for
enterprises, researchers and academia involved in Actinobacteria,
secondary metabolite production and industrial applications. This
book reviews the evolution of almost sixty years of development,
initially focused on amino acid production, which unleashes the
idea of C. glutamicum as a biorefinery due to its ability to
generate hundreds of products demanded by the market.
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