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Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing (Hardcover, 2012)
Loot Price: R4,355
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Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing (Hardcover, 2012)
Series: Current Topics in Microbiology and Immunology, 353
Expected to ship within 10 - 15 working days
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The objective of this CTMI volume is to provide readers with a
foundation for understanding what ADARs are and how they act to
affect gene expression and function. Because A-to-I editing may
affect base-pairing and RNA structure, processes including
translation, splicing, RNA replication, and miR and siRNA silencing
may be affected. It also is becoming increasingly apparent that
ADARs may possess roles not only as enzymes that deaminate
adenosine to produce inosine in RNA substrates with double-stranded
character, but also as proteins independent of their catalytic
property. Future studies of ADARs no doubt will provide us with
additional surprises and new insights into the modulation of
biological processes by the ADAR family of proteins.
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