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Antimicrobial Peptides in Gastrointestinal Diseases (Paperback)
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Antimicrobial Peptides in Gastrointestinal Diseases (Paperback)
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Antimicrobial peptides (AMPs), including cathelicidins and
defensins are host defence peptides that carry out multiple roles
in the gastrointestinal (GI) tract. Antimicrobial Peptides in
Gastrointestinal Diseases presents knowledge about the
physiological functions and pharmacological actions of AMPs in
inflammation, cancer, and further infection of the GI tract. The
book provides coverage from the basic research to clinical
application for GI diseases. Current research and development of
AMPs is presented, opening the way for further work on these
peptides, not only in the context of GI diseases, but also for
similar pathologies in other organs. AMPs are key to the regulation
of human microbiome and second line defence in the GI mucosa,
prevent colonization of pathogens and modulation of innate response
to invading pathogens, and modify immunological reactions during
inflammatory processes and oncogenic development in the GI mucosa.
More importantly, AMPs possess diversified anti-microbial actions
against various infectious diseases in the GI tract. With these
physiological functions and pharmacological actions, AMPs have
significant potential as therapeutic agents for the treatment of
inflammation, cancer and further infection in the GI tract.
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