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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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The Autisms - Molecules to Model Systems (Hardcover)
Loot Price: R5,232
Discovery Miles 52 320
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The Autisms - Molecules to Model Systems (Hardcover)
Expected to ship within 12 - 17 working days
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The science of autism has seen tremendous breakthroughs in the past
few decades. A multitude of relatively rare mutations have been
identified to explain around 15 % of autism cases with many of
these genetic causes systematically examined in animal models. This
marriage of human genetics and basic neurobiology has led to major
advances in our understanding of how these genetic mutations alter
brain function and help to better understand the human disease.
These scientific approaches are leading to the identification of
potential therapeutic targets for autism that can be tested in the
very same genetic models and hopefully translated into novel,
rational therapies. The Autisms: Molecules to Model Systems
provides a roadmap to many of these genetic causes of autism and
clarifies what is known at the molecular, cellular, and circuit
levels. Focusing on tractable genetic findings in human autism and
painstakingly dissecting the underlying neurobiology, the book
explains, is the key to understanding the pathophysiology of autism
and ultimately to identifying novel treatments.
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