0
Your cart

Your cart is empty

Books > Science & Mathematics > Biology, life sciences > Biochemistry > Biochemical immunology

Buy Now

Lyophilized Biologics and Vaccines - Modality-Based Approaches (Hardcover, 2015 ed.) Loot Price: R4,695
Discovery Miles 46 950
Lyophilized Biologics and Vaccines - Modality-Based Approaches (Hardcover, 2015 ed.): Dushyant Varshney, Man Mohan Singh

Lyophilized Biologics and Vaccines - Modality-Based Approaches (Hardcover, 2015 ed.)

Dushyant Varshney, Man Mohan Singh

 (sign in to rate)
Loot Price R4,695 Discovery Miles 46 950 | Repayment Terms: R440 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide the reader through all crucial aspects, from biophysical and chemical stability considerations of proteins, analytical methods, advances in controlled ice nucleation and quality-by-design approaches, alternate drying technology, to latest regulatory, packaging and technology transfer considerations to develop a stable, safe and effective therapeutic protein, vaccine and biotechnology products. Lyophilized Biologics and Vaccines: Modality-Based Approaches is composed of four sections with a total of 17 chapters. It serves as a reference to all critical assessments and steps from early pre-formulation stages to product launch: Provides recent understanding of heterogeneity of protein environment and selection of appropriate buffer for stabilization of lyophilized formulations Details the latest developments in instrumental analysis and controlled ice nucleation technology Explains in-depth lyophilized (or dehydrated) formulation strategies considering diverse modalities of biologics and vaccines, including plasmid DNA and lipid-based therapeutics Details an exhaustive update on quality-by-design and process analytical technology approaches, illustrated superbly by case studies and FDA perspective Provides the latest detailed account of alternate drying technologies including spray drying, bulk freeze-drying and crystallization, supported exceptionally by case studies Provides a step-by-step guide through critical considerations during process scale-up, technology transfer, packaging and drug delivery device selection, for a successful lyophilization process validation, regulatory submission and product launch Chapters are written by one or more world-renowned leading authorities from academia, industry or regulatory agencies, whose expertise cover lyophilization of the diverse modalities of biopharmaceuticals. Their contributions are based on the exhaustive review of literature coupled with excellent hands-on experiences in laboratory or GMP setup, making this an exceptional guide to all stages of lyophilized or dehydrated product development.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Release date: May 2015
First published: 2015
Editors: Dushyant Varshney • Man Mohan Singh
Dimensions: 235 x 155 x 24mm (L x W x T)
Format: Hardcover - Cloth over boards
Pages: 401
Edition: 2015 ed.
ISBN-13: 978-1-4939-2382-3
Categories: Books > Science & Mathematics > Biology, life sciences > Biochemistry > Biochemical immunology
Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
Promotions
LSN: 1-4939-2382-X
Barcode: 9781493923823

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Immunohistochemistry - The Ageless…
Charles F. Streckfus Hardcover R3,319 Discovery Miles 33 190
Pneumocystis-carinii-Pneumonie bei…
Paul Herausgegeben Von Wenzel Hardcover R3,389 Discovery Miles 33 890
Handbook of HLA Typing Techniques
Kam M. Hui Paperback R10,214 Discovery Miles 102 140
An Introduction to Radioimmunoassay and…
T. Chard Hardcover R4,899 Discovery Miles 48 990
The Secret Body - How the New Science of…
Daniel M. Davis Hardcover R592 R530 Discovery Miles 5 300
Dna Deamination And The Immune System…
Nina Papavasiliou, Sebastian Fugmann, … Hardcover R2,456 Discovery Miles 24 560
Molecular Aspects of Innate and Adaptive…
Lisa Steiner, George T. Stevenson, … Hardcover R4,146 Discovery Miles 41 460
Molecular Evolution on Rugged…
Alan S Perelson Hardcover R4,317 Discovery Miles 43 170
Leong's Manual of Diagnostic Biomarkers…
Runjan Chetty, Kumarasen Cooper, … Hardcover R3,910 R3,678 Discovery Miles 36 780
Neutrophils, The: New Outlook For Old…
Dmitry I. Gabrilovich Hardcover R4,178 Discovery Miles 41 780
Methods in Cellular Immunology
Rafael Fernandez-Botran, Vaclav Vetvicka Paperback R5,154 Discovery Miles 51 540
11th Hour - Introduction to Immunology
JM Decker Paperback R1,227 Discovery Miles 12 270

See more

Partners