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Antiarrhythmic Drugs (Paperback, Softcover reprint of the original 1st ed. 1989)
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Discovery Miles 47 130
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Antiarrhythmic Drugs (Paperback, Softcover reprint of the original 1st ed. 1989)
Series: Handbook of Experimental Pharmacology, 89
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The development of a new antiarrhythmic drug involves many people
with disparate skills. The organic chemist who makes it is guided
not only by the structure-action relations of previous compounds,
but by anticipation of a requirement for a particular type of
action. In fact several of the best-known antiarrhythmics,
including lidocaine, mexiletine, amiodarone and verapamil, were
originally synthesized for other purposes. Physicians have to
determine whether the new drug works, and pharma cologists how it
works. For some years I have believed that there was room for a
work which could be understood by all these groups and which could
enlighten each about the point of view of the others. Thus when I
was invited by Springer-Verlag to prepare a volume in their series
Handbook of Experimental Pharmacology, I already had a firm
conception of what its form should be. In any multi-author work
there are two objectives which cannot always readily be reconciled.
The first is to select topics which would relate to each other in a
coherent manner. to give a logical and orderly shape to the volume
as a whole. The second is to offer authors the greatest possible
freedom to express themselves as they wish. When the general design
was complete, prospective contributors were invited to write
specific chapters, being provided with a complete list of their
coauthors and chosen topics, so that they could avoid overlap."
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