Advances in Cancer Research, Volume 71 (Hardcover)

Volume 71 of Advances in Cancer Research begins with Morgan and Kastan presenting data on the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to targets for improved cancer therapies. Kok "et all." Review the methodological advantages and limitations to localizing tumor suppressor genes, especially those on the short arm of chromosome 3. Peltomaki and de la Chapelle describe research on mismatch repair genes and their effects on colorectal cancer. McKenna and Cotter present findings on the functions and failures of apoptosis in the hematopoietic system. Ravitz and Wenner review TGF-B and how it controls and affects cell cycle progression in a variety of cell types. Andrew Simpson presents data on the mutation frequencies of microsatellites in human carcinogenesis. Naor and colleagues present research on a multitude of tumors expressing levels of CD44 and discuss how CD44 may be used as a target for cancer therapy. Luisa Villa discusses various aspects of HPV and the potential clinical use of HPV testing in cervical cancer prevention programs. Last, Disis and Cheever review the studies that define HER-2/neu specific immunity in patients with cancer and the current vaccine strategies for generating specific immunity.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Advances in Cancer Research
Release date:	May 1997
First published:	April 1997
Volume editors:	George F. Vande Woude • George Klein
Dimensions:	229 x 152 x 23mm (L x W x T)
Format:	Hardcover
Pages:	385
ISBN-13:	978-0-12-006671-1
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > Cytology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	0-12-006671-8
Barcode:	9780120066711

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