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Cellular and Molecular Aspects of Inflammation (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R2,842
Discovery Miles 28 420
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Cellular and Molecular Aspects of Inflammation (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: New Horizons in Therapeutics
Expected to ship within 10 - 15 working days
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The characterization of the cellular and molecular mechanisms that
mediate inflammation provides a foundation that supports future
studies that will de fine mechanisms more intimately. It encourages
substantial optimism about the opportunities to understand the
inflammatory process and to use that information to develop novel
therapeutic approaches. Recent progress has defined the cells that
mediate the inflammatory response, many of the inter cellular
transmitters, the receptors, signal transduction processes and
regula tory mechanisms. Thus, we now have the opportunity to
understand inflammation in pharmacologic terms and to attack the
key molecular targets to develop new therapeutics. Among the cells
involved in the inflammatory response are the lympho cytes,
neutrophils and endothelial cells. Maintenance of homeostasis, re
sponse to proinflammatory stimuli and pathophysiologic responses
are products of complex interactions between these and other
elements of the immune systems. Each of these cells displays a
variety of receptors to define the stimuli to which they respond.
The receptors displayed that the signal transduction processes and
cellular responses are regulated genetically and epigenetic ally .
The critical role of membranes and particularly the phospho lipid
components of the membranes is emphasized by recent studies."
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