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Oncogenes and Tumour Suppressors (Paperback)
Loot Price: R1,937
Discovery Miles 19 370
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Oncogenes and Tumour Suppressors (Paperback)
Series: Frontiers in Molecular Biology, 19
Expected to ship within 12 - 17 working days
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Oncogenes and tumour suppressor genes have been the focus of much
research because of their role not only in cancer but also in
normal cell growth and differentiation. Oncogenes and Tumour
Suppressors is a unique volume that brings together a team of
leading researchers to present and critically assess our current
knowledge. The book covers two major areas of interest: oncogenes
and signal transduction, and tumour supressors and cell cycle
control. Topics covered include the mechanisms of oncogene
perturbation; growth factors and their receptors in cell
transformation; oncogenic cytoplasmic protein tyrosine kinases; the
RAS/RAP/ERK signal transduction pathway; oncogenic transcription
factors; mammalian cell cycle control; the retinoblastoma gene
product and its relatives; the tumour suppressor gene p53; tumour
suppressors and the inheritance of cancer; the clinical relevance
of oncogenes. Oncogenes and Tumour Suppressors is a major review
work that provides an unparalleled summary of our current
understanding of this field as viewed by some of its leading
researchers. It is of interest to all those involved in research on
the cell cycle, signal transduction, and cancer biology. The book
is also an excellent reference source with over 1800 selected
citations to the primary literature.
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