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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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HIV-1 Latency (Paperback, Softcover reprint of the original 1st ed. 2018)
Loot Price: R2,833
Discovery Miles 28 330
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HIV-1 Latency (Paperback, Softcover reprint of the original 1st ed. 2018)
Series: Current Topics in Microbiology and Immunology, 417
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This volume summarizes recent advances in understanding the
mechanisms of HIV-1 latency, in characterizing residual viral
reservoirs, and in developing targeted interventions to reduce
HIV-1 persistence during antiretroviral therapy. Specific chapters
address the molecular mechanisms that govern and regulate HIV-1
transcription and latency; assays and technical approaches to
quantify viral reservoirs in humans and animal models; the complex
interchange between viral reservoirs and the host immune system;
computational strategies to model viral reservoir dynamics; and the
development of therapeutic approaches that target viral reservoir
cells. With contributions from an interdisciplinary group of
investigators that cover a broad spectrum of subjects, from
molecular virology to proof-of-principle clinical trials, this book
is a valuable resource for basic scientists, translational
investigators, infectious-disease physicians, individuals living
with HIV/AIDS and the general public.
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