HIV-1 Latency (Paperback, Softcover reprint of the original 1st ed. 2018)

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Current Topics in Microbiology and Immunology, 417
Release date:	December 2019
First published:	2018
Editors:	Guido Silvestri • Mathias Lichterfeld
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	248
Edition:	Softcover reprint of the original 1st ed. 2018
ISBN-13:	978-3-03-013214-9
Categories:	Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > HIV / AIDS Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-03-013214-5
Barcode:	9783030132149

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