Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis (Hardcover, 2012 ed.)

The human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apical-basolateral transport of maternal idiotype and anti-idiotype IgG, IgG-virus complexes. The selective maternal-fetal transport of epitope- and paratope-bearing entities can influence the developping fetal immune system during pregnancy. The bidirectional maternal-fetal transfer of cells are of even more importance during pregnancy. Maternal cells with latent viruses transport viruses without impairment of fetal development. Cells with premaligant and malignant genetic transformation are also transported to the fetus. Fetal and neonatal tumours are initiated by such cells in spite of the antitumour potential of fetal organism. On the contary, the fetal cells repair maternal tissue injouries and survive in the organisms of the recipients for decades. These possess new consequences for the neonatal immunity and organ transplatation surgery.

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	April 2012
First published:	2012
Editors:	Gyoergy Berencsi III
Dimensions:	235 x 155 x 26mm (L x W x T)
Format:	Hardcover
Pages:	464
Edition:	2012 ed.
ISBN-13:	978-9400742154
Categories:	Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics Books > Medicine > Clinical & internal medicine > Paediatric medicine > General Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General Promotions
LSN:	9400742150
Barcode:	9789400742154

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