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Advances and Technical Standards in Neurosurgery (Paperback, Softcover reprint of the original 1st ed. 2004)
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Advances and Technical Standards in Neurosurgery (Paperback, Softcover reprint of the original 1st ed. 2004)
Series: Advances and Technical Standards in Neurosurgery, 29
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Epilepsy surgery is defined as any neurosurgical intervention whose
pri- mary objective is to relieve medically intractable epilepsy
(European Fed- eration of Neurological Societies Task Force 2000).
The aim of epilepsy surgery is to reduce the number and intensity
of seizures, minimise neuro- logical morbidity and antiepileptic
drug (AED) toxicity, and improve quality of life. By definition,
epilepsy surgery does not include normal surgical treatment of
intracranial lesions where the primary goal is to di- agnose and
possibly remove the pathological target, often an advancing tumour.
In these patients, epileptic seizures are only one symptom of the
lesion and will be treated concomitantly as part of the procedure.
Temporal lobe epilepsy (TLE) is recognised as the most common type
of refractory, focal epilepsy. In one third of all cases the
neuronal systems responsible for the seizures that characterise
this form of epilepsy fail to respond to currently available AEDs
(Andermann F 2002). New imaging methods, especially magnetic
resonance imaging (MRI), identify localising abnormalities in an
increasing proportion of patients with intractable focal epilepsy.
Consequently, the accuracy of the preoperative diagnostic pro-
cedures has been significantly improved during the last decade; and
suit- able candidates for surgery can be selected more reliably.
Currently the main resources in most epilepsy surgery centres have
been used to evaluate candidates for TLE surgery.
General
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