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The Pigmentary System - Physiology and Pathophysiology (Hardcover, New)
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The Pigmentary System - Physiology and Pathophysiology (Hardcover, New)
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Our knowledge about the function of the melanocyte has expanded
beyond boundaries not previously imagined. The melanocyte is no
longer considered merely a factory for the production of the
pigment melanin. Old data do not contradict the new but must be
reinterpreted in light of modern concepts of molecular and cellular
biology, enzymology, biochemistry, chemistry, and physics. Diseases
of the pigmentary system must be understood in terms of modern
science. The editors, each with special knowledge of the pigmentary
system, have combined their expertise and talents to produce a book
that will serve as the ultimate resource for the study of all
aspects of pigment cell biology. There is no comprehensive,
scholarly reference available which compiles both old and new data
into a single source. This book fills that void. There are
monographs to assist dermatologists caring for individuals with
disorders of pigmentation, and textbooks with an introductory
chapter on the physiology of pigmentation and a clinical chapter on
the disorders manifested by common abnormalities of the pigmentary
system. These resources continue to be invaluable, however they are
written for a specific type and level of audience. This volume is
encyclopedic in scope, so that the biologist, chemist, cosmetic
scientist, and clinician, whether novice or sophisticated expert,
can peruse any section of the book with confidence that it contains
most of the worlds knowledge on pigmentation, including historical
work. The bibliographies are also prepared to be as comprehensive
and all-inclusive as possible. The first part of the book brings
together the molecular and cellular biology, biochemistry,
chemistry, physics, and physiology of the normal melanocyte as
known in the 1990s. The second part continues this theme,
presenting a comprehensive discussion of most disorders of
pigmentation described to date. Information about pathophysiology,
treatment and other clinical data is included. The goal of the
editors is to provide the ultimate reference for practicing
physicians who care for patients with the rarest or most common
disorders of pigmentation, the laboratory scientist studying
disease in order to help the study of basic processes which affect
the pigmentary system, and the cosmetic scientist who seeks
comprehensive information on the pharmacopoeia available for
treating pigmentary disorders. All specialists interested in some
aspect of the pigmentary system can seek current answers to
questions related to their work.
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