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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Glycobiology and Medicine (Paperback, Softcover reprint of the original 1st ed. 2003)
Loot Price: R1,584
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Glycobiology and Medicine (Paperback, Softcover reprint of the original 1st ed. 2003)
Series: Advances in Experimental Medicine and Biology, 535
Expected to ship within 10 - 15 working days
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Over the past decade significant advances in technology have opened
up the field of glycobiology. In particular, improved methods for
carbohydrate analysis have led to important biochemical
observations demonstrating that sugars play crucial roles in human
physiology. It is clear that many diseases are associated with
characteristic changes in glycosylation and furthermore, the
possibility of modulating glycan processing to treat disease is
beginning to be realised. This volume summarises some of the
important recent developments in "glycobiology and medicine. " We
highlighted some of the numerous areas in which there are
glycosylation dependant pathological mechanisms causing common
diseases. The next decade will undoubtedly see novel diagnostic and
therapeutic techniques originating from these observations. This
will significantly enhance our ability to combat infection and
diseases such as bacterial and viral infections, some cancers,
glycolipid storage disorders, systemic autoimmune disease and
disorders that involve cytokine related inflammatory mechanisms.
These topics were discussed at the 6th Jenner Glycobiology and
Medicine meeting. This meeting received a European Commission
Education grant (No. HPCF-2002-00250). CONTENTS Glycosylation
Dependent Bacterial Infections 1. A Sweet Coating-How Bacteria Deal
with Sugars ...3 Anthony P. Corfield, Rebecca Wiggins, Cathryn
Edwards, Neil Myerscough, Bryan F. Warren, Peter Soothill, Michael
R. Millar, and Patrick Horner 2. The Glycosylation of Airway Mucins
in Cystic Fibrosis and Its Relationship with Lung Infection by
Pseudomonas aeruginosa ...17 . Philippe Roussel and Genevieve
Lamblin 3. Structural Basis for Bacterial Adhesion in the Urinary
Tract...33 . . Jenny Berglund and Stefan D.
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