Platelet-Rich Plasma (PRP) has gained tremendous popularity in
recent years as a treatment option for specialties including
Orthopedics, Dentistry, Sports Medicine, Otorhinolaryngology,
Neurosurgery, Ophthalmology, Urology, Vascular, Cardiothoracic and
Maxillofacial Surgery, and Veterinarian Medicine. Nowadays, PRP and
Stem Cell Science have added an exciting dimension to tissue
repair.
This book begins by giving the reader a broad overview of
current progress as well as a discussion of the technical aspects
of preparation and therapeutic use of autologous PRP. It is
followed by a review of platelet structure, function and major
growth factors in PRP (PDGF and TGF ).The third chapter outlines
the basic principles of biochemical cellular metabolism that
increases the efficacy of PRP. Analogous to the preparation of soil
for a garden, restoring cellular health should be the first
consideration in Regenerative Medicine. Standardization of PRP
preparation to clinical use still remains a challenging prospect.
In this sense, a feasible strategy for studying PRP preparation is
illustrated, which also allows to modulate and tailor the quality
of PRP for further clinical applications.
The science behind PRP and stem cells, on tissue regeneration,
cell proliferation and mesenchyme stem-cells are emphasized and
reviewed. Various specific uses of PRP are described with detailed
illustrations of various personal experiences mainly in orthopedic
injuries, ligament and tendon repair, degenerative diseases, sports
medicine, chronic wound healing as well as rehabilitation aspects
in tendinopathy.
Expertly written by leading scientists in the field, this book
provides for beginners and experienced readers scientific
fundamentals, the state of art of PRP, specific uses and personal
experiences with a practical approach and reference for current
trends in use. Finally, this book paves the way for future
developments."
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