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Books > Medicine > Clinical & internal medicine > Renal medicine
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Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance (Hardcover, 1st ed. 2016)
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Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance (Hardcover, 1st ed. 2016)
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Recent work has begun to elucidate at the molecular level how
albumin is handled by the kidney and how albuminuria develops in
various proteinuric diseases including minimal change disease and
focal segmental glomerulosclerosis. This volume provides a
comprehensive overview of the renal handling of albumin - from
basic mechanisms to the pathophysiology of proteinuric diseases. In
describing the basic mechanisms of albuminuria, a particular
highlight will be the focus on advanced imaging techniques such as
intravital microscopy that have allowed a detailed "window" into
albumin transit through the kidney. The volume will cover the
epidemiological studies which show that albuminuria is a strong and
independent marker of kidney disease progression and cardiovascular
events, the molecular details of albumin handling in the kidney at
the level of the glomerulus and the proximal tubule and the
pathophysiology of proteinuric diseases including minimal change
disease, membranous nephropathy, focal segmental glomerulosclerosis
and diabetic nephropathy.
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