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Stem Cells and Cancer Stem Cells, Volume 6 - Therapeutic Applications in Disease and Injury (Hardcover, 2012 ed.)
Loot Price: R5,695
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Stem Cells and Cancer Stem Cells, Volume 6 - Therapeutic Applications in Disease and Injury (Hardcover, 2012 ed.)
Series: Stem Cells and Cancer Stem Cells, 6
Expected to ship within 10 - 15 working days
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The difference among pluripotent stem cells, multipotent stem
cells, and unipotent stem cells is pointed out. Vast therapeutic
applications of the following specific stem cells in disease and
tissue injury are discussed: human embryonic stem cells, human
mesenchymal stem cells, germ cell-derived pluripotent stem cells,
induced pluripotent stem cells, human umbilical cord blood-derived
stem cells, breast tumor stem cells,and hematopoietic stem cells.
Because of the potential of human embryonic stem cells to produce
unlimited quantities of any human cell type, considerable focus is
placed on their therapeutic potential. Because of their
pluripotency, these cells have been used in various applications
such as tissue engineering, regenerative medicine, pharmacological
and toxicological studies, and fundamental studies of cell
differentiation. The formation of embryoid bodies, which are
three-dimensional aggregates of embryonic stem cells, is explained
as this is the first step in cell differentiation. Such embryoid
body culture has been widely used as a trigger for the in vitro
differentiation of embryonic stem cells. The basic capacity of
self-renewal of human embryogenic stem cells is explained. The role
of TGF-beta in the propagation of human embryonic stem cells is
discussed. The differentiation of human embryonic stem cells into
neurons, hepatocytes, cardiomyocytes, and retinal cells is fully
explained. Donor policies for hematopoietic stem cells are also
explained.
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