The volumes in this authoritative series present a
multidisciplinary approach to modeling and simulation of flows in
the cardiovascular and ventilatory systems, especially multiscale
modeling and coupled simulations. The cardiovascular and
respiratory systems are tightly coupled, as their primary function
is to supply oxygen to and remove carbon dioxide from the body's
cells. Because physiological conduits have deformable and reactive
walls, macroscopic flow behavior and prediction must be coupled to
phenomenological models of nano- and microscopic events in a
corrector scheme of regulated mechanisms when the vessel lumen
caliber varies markedly. Therefore, investigation of flows of blood
and air in physiological conduits requires an understanding of the
biology, chemistry, and physics of these systems together with the
mathematical tools to describe their functioning.
Volume 4 is devoted to major sets of intracellular mediators that
transmit signals upon stimulation of cell-surface receptors.
Activation of signaling effectors triggers the release of
substances stored in cellular organelles and/or gene transcription
and protein synthesis. Complex stages of cell signaling can be
studied using proper mathematical models, once the role of each
component is carefully handled. Volume 4 also reviews various
categories of cytosolic and/or nuclear mediators and illustrates
some major signal transduction pathways, such as NFkappaB axis,
oxygen sensing, and mechanotransduction."
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!