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Sensory Nerves and Neuropeptides in Gastroenterology - From Basic Science to Clinical Perspectives (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R5,710
Discovery Miles 57 100
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Sensory Nerves and Neuropeptides in Gastroenterology - From Basic Science to Clinical Perspectives (Paperback, Softcover reprint of the original 1st ed. 1991)
Series: Advances in Experimental Medicine and Biology, 298
Expected to ship within 10 - 15 working days
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In the past 15 years much evidence has accumulated which indicates
the paramount importance of sensory nerves in reg ulating functions
of the gastrointestinal tract. In parallel, the attention of
researchers in this field has been increas ingly attracted to the
role played by neuropeptides in the normal and diseased gut. Basic
research on the peculiar properties of capsaicin, the pungent
ingredient from plants of the genus Capsicum, has allowed the gap
between these two areas of research to be bridged. Sincethen, the
study of gut afferents and neuropeptides has become more and more
interconnected and recognized as a major avenue to understand ing
the pathophysiology of various human diseases. It is widely
recognized that a certain subset of primary afferents synthesize,
store and release neuropeptides (such as tachykin nins and
calcitonin gene-related peptide) from their central and peripheral
endings, the latter being widely distributed in the alimentary
canal and related organs (liver, pancreas). The First International
Meeting on Sensory Nerves and Neuropeptides in Gastroenterology,
held in Florence from December 4-5, 1989, sponsored and organized
by Fondazione Internazionale Menarini, aimed to focus the current
status of research in this field. The contributions presented at
the meeting and in this book delineate a suggestive scenario in
which sensory nerves of the gut, and the multiple messages they
carry through the release of neuropeptides, are to be considered as
a major target for the development of new drugs potentially useful
in a number of diseases of the gastro intestinal tract."
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