Surface-Enhanced Raman Spectroscopy - Bioanalytical, Biomolecular and Medical Applications (Hardcover, 1st ed. 2016)

This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Biological and Medical Physics, Biomedical Engineering
Release date:	December 2015
First published:	2016
Authors:	Marek Prochazka
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Hardcover
Pages:	221
Edition:	1st ed. 2016
ISBN-13:	978-3-319-23990-3
Categories:	Books > Medicine > Other branches of medicine > Medical imaging > Radiology Books > Science & Mathematics > Chemistry > Analytical chemistry > Qualitative analytical chemistry > Chemical spectroscopy, spectrochemistry > General
LSN:	3-319-23990-2
Barcode:	9783319239903

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