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Methods for Studying Nucleic Acid/Drug Interactions (Paperback)
Loot Price: R1,885
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Methods for Studying Nucleic Acid/Drug Interactions (Paperback)
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Since most therapeutic efforts have been predominantly focused on
pharmaceuticals that target proteins, there is an unmet need to
develop drugs that intercept cellular pathways that critically
involve nucleic acids. Progress in the discovery of nucleic acid
binding drugs naturally relies on the availability of analytical
methods that assess the efficacy and nature of interactions between
nucleic acids and their putative ligands. This progress can benefit
tremendously from new methods that probe nucleic acid/ligand
interactions both rapidly and quantitatively. A variety of novel
methods for these studies have emerged in recent years, and Methods
for Studying DNA/Drug Interactions highlights new and
non-conventional methods for exploring nucleic acid/ligand
interactions. Designed to present drug-developing companies with a
survey of possible future techniques, the book compares their
drawbacks and advantages with respect to commonly used tools.
Perhaps more importantly, this book was written to inspire young
scientists to continue to advance these methods into fruition,
especially in light of current capabilities for assay
miniaturization and enhanced sensitivity using microfluidics and
nanomaterials.
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