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The Hippo Signaling Pathway and Cancer (Hardcover, 2013 ed.)
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The Hippo Signaling Pathway and Cancer (Hardcover, 2013 ed.)
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The Hippo signaling pathway is rapidly gaining recognition as an
important player in organ size control and tumorigenesis, and many
leading scientists are showing increased interest in this growing
field and it's relation to cancer. The chapters in this volume
cover virtually all aspects of tumor biology, because members of
the Hippo Pathway have been associated with numerous
well-established cell signaling pathways, just to name a few; Ras,
Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely
involved in regulating "classic" tumor characteristics such as cell
proliferation, survival and growth, but is also diversely involved
in cell-autonomous and non-cell-autonomous differentiation,
migration and organ size control. The primary audience are
researchers interested in basic science in the areas of tumor
suppression, cell cycle and size regulation, development and
differentiation.
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