This book presents the latest findings in mechanosensitivity of
the nervous system. The nervous system stands out from a number of
tissues because besides reacting to the mechanical stress it is
transmitting its own response to other organs and tissues, which
are located downstream of its signaling pathway. For this reason
any type of mechanical stimulation of the nervous system, which is
capable of triggering a physiological response, has high scientific
and practical significance, since it allows its use beyond a
particular experimental model anywhere where it is contributing to
a particular pathological condition.
This book is a unique collection of reviews outlining the
current knowledge and the future developments in this rapidly
growing field. Currently, investigations of the effects of
mechanical stress on the nervous system are focused on several
issues. The majority of studies investigate the effects of
mechanical stimulation on mechanosensitive channels, as its primary
target and interactive agent, and aim on description of downstream
intracellular signaling pathways together with addressing general
issues of biomechanics of the nervous system. Knowledge of
biomechanics, and mechanisms, which underlie it on organism, organ,
tissue and cellular level, is necessary for understanding of the
normal functioning of living organisms and allows to predict
changes which arise due to alterations of their environment, and
possibly will allow to develop new methods of artificial
intervention.
The book brings up the problem closer to the experts in related
medical and biological sciences as well as practicing doctors
besides just presenting the latest achievements in the field.
General
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