0
Your cart

Your cart is empty

Books > Professional & Technical > Biochemical engineering > Biotechnology

Buy Now

Applications of Aminoacylation Ribozymes That Recognize the 3'-end of tRNA (Paperback, Softcover reprint of the original 1st ed. 2017) Loot Price: R3,120
Discovery Miles 31 200
Applications of Aminoacylation Ribozymes That Recognize the 3'-end of tRNA (Paperback, Softcover reprint of the original...

Applications of Aminoacylation Ribozymes That Recognize the 3'-end of tRNA (Paperback, Softcover reprint of the original 1st ed. 2017)

Naohiro Terasaka

Series: Springer Theses

 (sign in to rate)
Loot Price R3,120 Discovery Miles 31 200 | Repayment Terms: R292 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

In this thesis, applications of aminoacylation ribozymes named flexizymes are described. Flexizymes have the following unique characteristics: (i) substrate RNA is recognized by two consecutive base pairs between the 3'-end of substrate RNA and the 3'-end of the flexizyme; (ii) these base pairs can be substituted with other base pairs; and (iii) various activated amino acids can be used as substrates including both canonical and noncanonical amino acids. This flexible aminoacylation of RNAs by flexizymes was used to label endogenous tRNAs to be removed, and in vitro selection using the tRNA-depleted library enabled the discovery of the novel interaction between the microRNA precursor and metabolites. Flexizymes are also used to prepare various aminoacyl-tRNAs bearing mutations at the 3'-end to engineer the translation machinery and to develop the orthogonal translation machinery. The first part of the research demonstrated that SELEX is appropriate for discovering the interaction between small RNA and ligands, and suggested that more RNA motif binding to small molecules exists in small RNAs. The second part opened a door to new opportunities for in vitro synthetic biology involving the engineering of the genetic codes and translation machineries. This research also indicated the great potential of aminoacylation by flexizymes to be applied in various fields of RNA research, which is beneficial for RNA researchers.

General

Imprint: Springer Verlag,Japan
Country of origin: Japan
Series: Springer Theses
Release date: July 2018
First published: 2017
Authors: Naohiro Terasaka
Dimensions: 235 x 155 x 6mm (L x W x T)
Format: Paperback
Pages: 89
Edition: Softcover reprint of the original 1st ed. 2017
ISBN-13: 978-4-431-56809-4
Categories: Books > Science & Mathematics > Chemistry > Physical chemistry > Catalysis
Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
Books > Professional & Technical > Biochemical engineering > Biotechnology > General
Promotions
LSN: 4-431-56809-3
Barcode: 9784431568094

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Advanced Nanoformulations - Theranostic…
Md Saquib Hasnain, Amit Kumar Nayak, … Paperback R4,223 Discovery Miles 42 230
Frontiers in Aquaculture Biotechnology
W. S. Lakra, Mukunda Goswami, … Paperback R4,171 Discovery Miles 41 710
Encyclopedia of Sensors and Biosensors
Roger J Narayan Hardcover R54,522 Discovery Miles 545 220
Cyanobacterial Lifestyle and its…
Prashant Kumar Singh, Maria F. Fillat, … Paperback R4,171 Discovery Miles 41 710
Comprehensive Foodomics
Alejandro Cifuentes Hardcover R56,868 Discovery Miles 568 680
Targeting Chronic Inflammatory Lung…
Kamal Dua, Philip M. Hansbro, … Paperback R4,285 Discovery Miles 42 850
Comprehensive Biotechnology
Murray Moo- Young Hardcover R73,488 Discovery Miles 734 880
Statistical, Mapping and Digital…
Gilles Maignant, Pascal Staccini Hardcover R2,333 Discovery Miles 23 330
Cognitive Prosthethics
Maxime Derian Hardcover R3,665 Discovery Miles 36 650
Advances in Applied Microbiology, Volume…
Geoffrey M. Gadd, Sima Sariaslani Hardcover R3,286 Discovery Miles 32 860
New and Future Developments in Microbial…
H. B Singh, Vijai G. Gupta, … Hardcover R5,102 R4,730 Discovery Miles 47 300
Enzymes in Food Biotechnology…
Mohammed Kuddus Paperback R6,760 R6,376 Discovery Miles 63 760

See more

Partners