Cancer Therapy - Differentiation, Immunomodulation and Angiogenesis (Paperback, Softcover reprint of the original 1st ed. 1993)

Provided here is a comprehensive examination of the basic and clinical condition of three innovative and promising approaches to cancer therapy, which may support or even substitute chemotherapy: differentiation, immunomodulation, and inhibition of angiogenesis. Differentiation shouldnormalize neoplastic cells and make them compatible with the host. Its feasibility with retinoids, interferons, chemotherapeutic and other agents is discussed. Modulation by biological agents, cytotoxic effector cells and drugs is considered in attempts to boost endogenous antitumour defenses and/or to render neoplastic cells more susceptible to the immune attack of the host. Finally, the important aspect of interfering with tumour blood vessel development and function is taken into account. Consideringthe importance that chemotherapy has in cancer treatment and in view of a more and more integrated strategy, the relationship between the aforementioned approaches and chemotherapeutic agents and chemoresistance is treated in detail.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Nato ASI Subseries H:, 75
Release date:	December 2011
First published:	1993
Editors:	Natale D'Alessandro • Enrico Mihich • Luciano Rausa • Haim Tapiero • Thomas R. Tritton
Dimensions:	235 x 155 x 16mm (L x W x T)
Format:	Paperback
Pages:	288
Edition:	Softcover reprint of the original 1st ed. 1993
ISBN-13:	978-3-642-84615-1
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-642-84615-7
Barcode:	9783642846151

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