Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function
and Links to Other Neuropathologies focuses on unresolved or
emerging issues concerning the role of chemokine receptors in
neuronal injury and HIV neuropathology, including their ability to
regulate fundamental neuronal and glial functions and their role in
neurovirulence and neurotoxicity. Although the importance of these
molecules in the CNS physiology and pathology is now apparent,
these issues are still matter of debate, and further research is
required to design effective pharmacological agents that
specifically target the brain chemokine system without major side
effects. To this end, specific topics have been selected and are
reviewed by international experts within the basic science/medical
community. This book encourages investigation in the most
controversial areas and fosters interaction between clinicians and
basic scientists. The book also increases awareness about
differences in disease progression among different parts of the
world as well as selected patient populations, which may also help
identifying novel therapeutic strategies.
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