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Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer (Hardcover, 1st ed. 2021)
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Discovery Miles 40 470
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Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer (Hardcover, 1st ed. 2021)
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This book gives insight into the functional role of non-coding RNAs
in central pathways contributing to the development of obesity,
type 2 diabetes, non-alcoholic fatty liver disease,
atherosclerosis, myocardial infarction, cardiomyopathy, and heart
failure. It also sheds light on the relationship of this cluster
with cancer. Tumor cells, in contrast to cells in cardiometabolic
tissues, can regulate this cluster of non-coding RNAs to escape
from oxidative stress and anti-tumor immunity and maintain insulin
sensitivity, facilitating cancer progression. The book presents a
cluster of non-coding RNAs that may be prospectively analyzed in
extensive cohort studies to determine their value in
risk-predicting machine learning algorithms. In addition, it
emphasizes the role of microvesicles in communication between
tumor-adjacent tissue, inflammatory cells, and tumor cells, with a
special focus on the role of miR-155. The book intends to promote
interdisciplinary research. Due to the comprehensive background
information provided in each chapter, it is suitable for
researchers in academia and industry and for graduate students in
biology, bioengineering, and medicine.
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