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Modern CNS Drug Discovery - Reinventing the Treatment of Psychiatric and Neurological Disorders (Hardcover, 1st ed. 2021)
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Modern CNS Drug Discovery - Reinventing the Treatment of Psychiatric and Neurological Disorders (Hardcover, 1st ed. 2021)
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This textbook provides a comprehensive overview of the currently
used concepts, approaches and technologies in the discovery and
development of new treatments for the full spectrum of disorders of
the central nervous system. It guides the reader through all
essential steps, from finding an innovative idea, to the
registration of a new drug. Divided into four sections, the book
starts by presenting a broad perspective on current approaches in
central nervous system (CNS) drug discovery. The second section
addresses the generation of ideas for the identification of targets
and novel treatment strategies; covers core functions in early
discovery, and provides an example of a novel treatment paradigm:
brain stimulation. The third section highlights strategies and
technologies in translational CNS drug discovery. In an effort to
bridge the gap between discovery and clinical development, it also
covers brain imaging, EEG and cognitive testing approaches. The
fourth section extensively discusses the clinical phase of drug
development, covering the basics of early clinical testing for
psychopharmacological drugs. The book's final chapter addresses the
registration for newly developed drugs. Written by experts from
academia and industry, the book covers important basics and best
practices, as well as recent developments in drug discovery.
Offering in-depth insights into the world of drug development, it
represents essential reading for early researchers who want to
prepare for a career in drug discovery in academia or industry.
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