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Books > Science & Mathematics > Chemistry > Physical chemistry > Quantum & theoretical chemistry
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Melanin Chemistry Explored by Quantum Mechanics - Investigations for Mechanism Identification and Reaction Design (Hardcover, 1st ed. 2021)
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Melanin Chemistry Explored by Quantum Mechanics - Investigations for Mechanism Identification and Reaction Design (Hardcover, 1st ed. 2021)
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This book discusses recent advances in theoretical-computational
studies on the biosynthesis of melanin pigment (melanogenesis).
These advances are being driven by the development of
high-performance computers, new experimental findings, and
extensive work on medical applications involving the control of
pigmentation and the treatment of challenging dermatological
diseases. Understanding the elementary processes involved in
chemical reactions at the atomic scale is important in biochemical
reaction design for effective control of the pigmentary system.
Accordingly, the book focuses on the elementary steps involved in
melanogenesis, which crucially affect the composition of the
resulting melanin pigment by means of competitive reactions. The
book also addresses reactions analogous to melanogenesis, with a
focus on o-quinone reactions, which are especially important for
understanding melanogenesis-associated cytotoxicity.
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