DNA microarray technology has become a useful technique in gene
expression analysis for the development of new diagnostic tools and
for the identification of disease genes and therapeutic targets for
human cancers. Appropriate control for DNA microarray experiment
and reliable analysis of the array data are key to performing the
assay and utilizing the data correctly. The most difficult
challenge has been the lack of a powerful method to analyze the
data for all genes (more than 30,000 genes) simultaneously and to
use the microarray data in a decision-making process. In this book,
the authors describe DNA microarray technology and data analysis by
pointing out current advantages and disadvantages of the technique
and available analytical methods. Crucially, new ideas and
analytical methods based on the authors' own experience in DNA
microarray study and analysis are introduced. It is believed that
this new way of interpreting and analyzing microarray data will
bring us closer to success in decision-making using the information
obtained through the DNA microarray technology.
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