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The Macrophage as Therapeutic Target (Paperback, Softcover reprint of the original 1st ed. 2003) Loot Price: R7,691
Discovery Miles 76 910
The Macrophage as Therapeutic Target (Paperback, Softcover reprint of the original 1st ed. 2003): Siamon Gordon

The Macrophage as Therapeutic Target (Paperback, Softcover reprint of the original 1st ed. 2003)

Siamon Gordon

Series: Handbook of Experimental Pharmacology, 158

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Loot Price R7,691 Discovery Miles 76 910 | Repayment Terms: R721 pm x 12*

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During the past decade, the rapid growth of molecular and cellular knowledge of macrophages, as a specialized host defense and homeostatic system, has begun to offer attractive targets for therapeutic intervention. Macrophages play a central role in a wide range of disease processes, from genetically determined lysosomal storage diseases, to acute sepsis, chronic inflammation and repair, tissue injury and cell death. Under- or overactivity of macrophage clearance, immune effector functions and responses to metabolic abnormalities contribute to common disorders such as autoimmunity, atherosclerosis, Alzheimer s disease and major infections including AIDS and Tuberculosis. Whilst the goals of therapeutic intervention based on improved understanding of macrophage functions and their contribution to pathogenesis may seem self evident, there are considerable difficulties in producing useful new agents.

The present volume covers a range of subjects and provides opportunities for a more focused macrophage-targeted approach. The individual chapters review selected topics briefly, to place cellular processes and molecular targets in perspective. Overall, the volume should provide a broad sample of the state of the art. Useful reviews and references in the literature are cited within individual chapters."

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Handbook of Experimental Pharmacology, 158
Release date: October 2012
First published: 2003
Editors: Siamon Gordon
Dimensions: 235 x 155 x 26mm (L x W x T)
Format: Paperback
Pages: 496
Edition: Softcover reprint of the original 1st ed. 2003
ISBN-13: 978-3-642-62919-8
Categories: Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology
Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
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LSN: 3-642-62919-9
Barcode: 9783642629198

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