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Heredity under the Microscope - Chromosomes and the Study of the Human Genome (Paperback)
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Heredity under the Microscope - Chromosomes and the Study of the Human Genome (Paperback)
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By focusing on chromosomes, Heredity under the Microscope offers a
new history of postwar human genetics. Today chromosomes are
understood as macromolecular assemblies and are analyzed with a
variety of molecular techniques. Yet for much of the twentieth
century, researchers studied chromosomes by looking through a
microscope. Unlike any other technique, chromosome analysis offered
a direct glimpse of the complete human genome, opening up seemingly
endless possibilities for observation and intervention. Critics,
however, countered that visual evidence was not enough and pointed
to the need to understand the molecular mechanisms. Telling this
history in full for the first time, Soraya de Chadarevian argues
that the often bewildering variety of observations made under the
microscope were central to the study of human genetics. Making
space for microscope-based practices alongside molecular
approaches, de Chadarevian analyzes the close connections between
genetics and an array of scientific, medical, ethical, legal, and
policy concerns in the atomic age. By exploring the visual evidence
provided by chromosome research in the context of postwar biology
and medicine, Heredity under the Microscope sheds new light on the
cultural history of the human genome.
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