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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Microstructural Parcellation of the Human Cerebral Cortex - From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging (Hardcover, 2013 ed.)
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Microstructural Parcellation of the Human Cerebral Cortex - From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging (Hardcover, 2013 ed.)
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Unraveling the functional properties of structural elements in the
brain is one of the fundamental goals of neuroscientific research.
In the cerebral cortex this is no mean feat, since cortical areas
are defined microstructurally in post-mortem brains but
functionally in living brains with electrophysiological or
neuroimaging techniques - and cortical areas vary in their
topographical properties across individual brains. Being able to
map both microstructure and function in the same brains
noninvasively in vivo would represent a huge leap forward. In
recent years, high-field magnetic resonance imaging (MRI)
technologies with spatial resolution below 0.5 mm have set the
stage for this by detecting structural differences within the human
cerebral cortex, beyond the Stria of Gennari. This provides the
basis for an in vivo microanatomical brain map, with the enormous
potential to make direct correlations between microstructure and
function in living human brains. This book starts with Brodmann's
post-mortem map published in the early 20th century, moves on to
the almost forgotten microstructural maps of von Economo and
Koskinas and the Vogt-Vogt school, sheds some light on more recent
approaches that aim at mapping cortical areas noninvasively in
living human brains, and culminates with the concept of "in vivo
Brodmann mapping" using high-field MRI, which was introduced in the
early 21st century.
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