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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology

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Heat Shock Proteins in Cancer (Paperback, Softcover reprint of hardcover 1st ed. 2007) Loot Price: R5,462
Discovery Miles 54 620
Heat Shock Proteins in Cancer (Paperback, Softcover reprint of hardcover 1st ed. 2007): Stuart K. Calderwood, Michael Y....

Heat Shock Proteins in Cancer (Paperback, Softcover reprint of hardcover 1st ed. 2007)

Stuart K. Calderwood, Michael Y. Sherman, Daniel R. Ciocca

Series: Heat Shock Proteins, 2

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Loot Price R5,462 Discovery Miles 54 620 | Repayment Terms: R512 pm x 12*

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Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

General

Imprint: Springer
Country of origin: Netherlands
Series: Heat Shock Proteins, 2
Release date: November 2010
First published: 2007
Editors: Stuart K. Calderwood • Michael Y. Sherman • Daniel R. Ciocca
Dimensions: 235 x 155 x 21mm (L x W x T)
Format: Paperback
Pages: 400
Edition: Softcover reprint of hardcover 1st ed. 2007
ISBN-13: 978-90-481-7627-4
Categories: Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 90-481-7627-1
Barcode: 9789048176274

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