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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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The Blood-Brain and Other Neural Barriers - Reviews and Protocols (Hardcover, Edition.)
Loot Price: R5,566
Discovery Miles 55 660
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The Blood-Brain and Other Neural Barriers - Reviews and Protocols (Hardcover, Edition.)
Series: Methods in Molecular Biology, 686
Expected to ship within 10 - 15 working days
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Evolving technologies starting with tracer studies, and more
recently with genomics and proteomics, have provided novel
information about the molecular properties of cerebral endothelium
and astrocytes; however, further studies must be done in animal
models of neurological diseases and in humans to get a clearer
understanding of the pathogenesis of blood-brain barrier (BBB)
breakdown in nervous system diseases. In The Blood-Brain and Other
Neural Barriers: Reviews and Protocols, experts in the field
present a series of cutting-edge protocols which can be used to
study the barriers. Opening with detailed information on components
of the neurovascular unit as well as the blood-cerebrospinal,
blood-retinal, and blood-nerve barriers, the book continues with
meticulous techniques to image the barriers in humans and
experimental animals, followed by cutting-edge molecular techniques
to study the BBB and novel models to study the barriers, and it
concludes with techniques for the delivery of therapeutic agents
across the BBB. Written in the highly successful Methods in
Molecular Biology(TM) series format, protocol chapters include
introductions to their respective topics, lists of the necessary
materials, step-by-step, readily reproducible laboratory protocols,
and tips on troubleshooting and avoiding known pitfalls.
Authoritative and up-to-date, The Blood-Brain and Other Neural
Barriers: Reviews and Protocols will aid the research efforts of
not only graduate students but also more experienced investigators
and support future studies of these vital systems.
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