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Polymer Membranes/Biomembranes (Paperback, 2010 ed.)
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Polymer Membranes/Biomembranes (Paperback, 2010 ed.)
Series: Advances in Polymer Science, 224
Expected to ship within 10 - 15 working days
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Themulticomponentnatureofbiologicalmembranesandtheirintra-
andextracel- lar interactions make direct investigations on the
membrane structure and processes nearly impossible. Clearly, a
better understanding of the membrane properties and the mechanisms
determining membrane protein functions is crucial to the imp-
mentation of biosensors, bioreactors and novel platforms for
medical therapy. For this reason, the interest in model systems
suitable for the construction and study of complex lipid/protein
membrane architectures has increased steadily over the years. The
classical portfolio of model membranes used for biophysical and -
terfacial studies of lipid (bi)layers and lipid/protein composites
includes Langmuir monolayers assembled at the water/air interface,
(uni- and multi-lamellar) vesicles in bulk (liposomal) dispersion,
bimolecular lipid membranes (BLMs), and various types of
solid-supported membranes. All these have speci?c advantages but
also suffer from serious drawbacksthat limit their technical
applications. Polymer m- branes comprised of entirely synthetic or
hybrid (synthetic polymer/biopolymer) block copolymersappeared to
be an attractive alternative to the lipid-based models. Generally,
the synthetic block copolymer membranes are thicker and more stable
and the versatility of polymer chemistry allows the adoption of
relevant properties for a wide range of applications. This volume
provides a vast overview of the physico-chemical and synthetic -
pectsofarti?cial membranes.
Numerousmembranemodelsaredescribed,including their properties(i. e.
swelling, drying,lateral mobility,stability, electrical conduct-
ity, etc. ), advantages, and drawbacks. The potential applications
of these models are discussed and supported by real examples.
Chapter 1 summarizesmethodsfor the stabilizationof arti?cial lipid
membranes.
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