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Drug Delivery with Targeted Nanoparticles - In Vitro and In Vivo Evaluation Methods (Hardcover)
Loot Price: R11,703
Discovery Miles 117 030
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Drug Delivery with Targeted Nanoparticles - In Vitro and In Vivo Evaluation Methods (Hardcover)
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Nanotechnology has the potential to change every part of our lives.
Today, nanotechnology-based products are used in many areas, and
one of the most important areas is drug delivery. Nanoparticulate
drug delivery systems not only provide controlled delivery of drugs
and improved drug solubility but also improve drug efficiency and
reduce side effects via targeting mechanisms. However, compared
with conventional drug delivery systems, few nanoparticle-based
products are on the market and almost all are nontargeted or only
passively targeted systems. In addition, obtaining targeted
nanoparticle systems is quite complex and requires several
evaluation mechanisms. This book discusses the production,
characterization, regulation, and currently marketed targeted
nanoparticle systems in a broad framework. It provides an overview
of targeted nanoparticles' (i) in vitro characterization, such as
particle size, stability, ligand density, and type; (ii) in vivo
behavior for different targeting areas, such as tumor, brain, and
vagina; and (iii) current advances in this field, including
clinical trials and regulation processes.
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