First published in 1990, this indispensable volume brings together authoritative, up-to-date, critical accounts of the present status of positron emission tomography (PET) in the study of movement disorders both in terms of the basic science relevant to PET and the clinical science related to the study of specific disease processes. For better understanding, it includes a review of the basic principles of PET and tracer kinetics. It also reviews clinical studies concerning Parkinson's and Huntington's disease, as well as some of the less common movement disorders such as progressive supranuclear palsy, olivopontocerebellar atrophy, and dystonia. Throughout the text, it emphasizes PET as a tool for the quantitative measurement of meaningful biochemical and physiological processes. This state-of-the-art work provides a perspective concerning the degree to which PET studies have advanced knowledge and the future role anticipated for PET. All clinical and basic researchers interested in functional imaging with PET and movement disorders will find this book an absolute must.

This Third Edition of Medical Cell Biology focuses on the scientific aspects of cell biology important to medical students, dental students, veterinary students, and prehealth undergraduates. Maintaining a primary focus on eukaryotic cell biology, the text explains general cell biology principles in the context of organ systems and human and animal disease.
* 60% New Material
* New Topics include:
Apoptosis and cell dealth from a neural perspective
Signal transduction as it relates to normal and abnormal heart function
Cell cycle and cell division related to cancer biology
* All new clinical cases
* Serves as a prep guide to the National Medical Board Exam with a CD-ROM of 200 sample board-style questions (using Exam Master(R) technology): www.exammaster.com
* Focuses on eukaryotic cell biology as it related to human disease, thus making the subject more accessible to pre-med and pre-health students

Comprehensive book on mitral stenosis not only compiles the existing published knowledge and literature about mitral stenosis in a succinct manner but also has input from experts having years of experience in this field. It will serve as an authentic reference and a ready reckoner for cardiology fellows, practicing cardiologists, academics and researchers

Acquire the 21st-century skills to succeed in A&P with a leading text in the field. Human Anatomy & Physiology, 12th edition by best-selling authors Elaine Marieb and Katja Hoehn is one of the leading texts in the field, aimed not only to support your learning every step of the way but also to motivate and inspire you as a future scientist in the field. An ideal learning resource both for novice and expert students, this text will equip you with the most up to date, 21st-century skills to succeed in A&P and beyond. Well-known for its engaging, conversational writing style, easy-to-follow figures, and unique clinical insights, this editioncontinues its tradition of innovation, with an array of compelling multimedia tools and visual presentations, along with questions and clinical case studies to cement your understanding of the topics. With this text you can: Master the challenging A&P terminology Practice your critical thinking and problem-solving skills Apply your knowledge to clinical scenarios Gain the knowledge required for entry into nursing, allied health, and exercise science programs. Personalise your learning experience and improve results with Mastering (R) A&P. Mastering provides access to trusted content using customisable tools, features, and assessments built for today's digital learners. Pearson Mastering (R) A&P is not included. If you would like to purchase both the physical text and Mastering A&P, search for: 9781292421957 Human Anatomy & Physiology, Global Edition, 12th edition with Mastering Biology The bundle consists of: 9781292421803 Human Anatomy & Physiology, Global Edition, 12th Edition 9781292421797 Pearson Mastering A&P- Instant Access - for Human Anatomy & Physiology, Global Edition 9781292421742 Pearson Mastering A&P with Pearson eText - Instant Access - for Human Anatomy & Physiology, Global Edition Mastering A&P should only be purchased when required by an instructor. Please be sure you have the correct ISBN and Course ID. Instructors, contact your Pearson representative for more information.

The author of a number of acclaimed, best-selling surgical atlases has collaborated again with an award-winning artist to produce another invaluable surgical resource. This highly regarded team provide a master-class in the demonstration of surgically relevant anatomy. Masquelet has attained world-renown in particular for his innovative flaps for reconstructive plastic surgery of the limbs, in this book he displays his unrivalled knowledge of surgery of the trunk, head, and neck. Every point of entry in required surgical procedures is described, and every procedure is illustrated with a sequence of drawings, displayed as the surgeon would see them, together with anatomical cross-sections.

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur, new possibilities emerge for limiting the effects of aging on neural function. A single source reference is necessary to keep abreast of the recent advances and future directions of gerontology research. Brain Aging: Models, Methods, and Mechanisms offers a selective overview of the research in this rapidly expanding field. A valuable resource for new and established investigators of the aging brain, this volume reviews critical studies of brain aging in new animal models, as well as advances in brain imaging techniques that permit investigations in aging humans with increasingly higher resolution. Detailed discussions link the information from human and animal studies to illustrate a comprehensive picture of the mechanism of aging. Emphasizing normal brain aging rather than pathological degeneration, the text provides an understanding of fundamental age-related changes in the nervous system and hypothesis-driven research into their basis. The book includes critical analyses of the distinct methodological challenges inherent in investigating the aging nervous system. Contributions from distinguished leaders and pioneers in their respective fields address data and mechanisms, as well as models and methods that are key to the study of aging. Each chapter is extensively referenced and highlights experimental concerns that are magnified or unique to the aging brain. Outlining relevant methods and techniques, this book provides scientists, researchers, and clinicians with a broad understanding of the important progress and implications for the future of this significant field.

As one of the first cortical areas to be explored experimentally, the motor cortex continues to be the focus of intense research. Motor Cortex in Voluntary Movements: A Distributed System for Distributed Functions presents developments in motor cortex research, making it possible to understand and interpret neural activity and use it to reconstruct movements. Featuring viewpoints based on monkey and human studies, the book focuses on how neuronal activity changes during learning, discusses what the motor cortex encodes for, and covers the neuronal representations of voluntary movements and the mechanism of their generation during learning. Section 1 uses functional neuroanatomy and imaging studies to describe motor cortical function, and Section 2 provides an overview of studies about neural representations in the motor cortex. The third section concentrates on motor learning, and the final section highlights the reconstruction of movements using brain activity. Revealing many exciting applications of this rapidly expanding science, this book enhances our understanding of the generation of motor commands. It is an essential resource for neuroscientists interested in motor function, rehabilitation medicine practitioners, and biomedical engineers.

This reference compiles the most current technical and biological data available to survey the state-of-science in the care and management of patients with bronchopulmonary dysplasia, COPD, and other forms of lung disease-tracking the initiation and progression of processes that cause airway obstruction, the biologic and physiological abnormalities that characterize COPD, and the potential reversibility of the inflammatory response in COPD for improved patient diagnosis and treatment.

This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC transplantation discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors details detection of bone marrow contamination by tumor cells and removal procedures focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors explores the effects of growth factor administration and leukapheresis on PB stem cell donors shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells employs automated fluorescence image cytometry to study early HSC behavior following seeding Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,

Disorders of the Autonomic Nervous System, the fifth volume in The Autonomic Nervous System book series, is a description of the disorders which give rise to autonomic failure and orthostatic hypotension. Each chapter is prepared by an international authority in the diagnosis and treatment of that disorder. The language and terminology are clear enough to promote understanding of the clinical problems and the underlying concepts of basic science. The most recent data, especially that derived from molecular biology, is included in the discussions of relevant diseases. Hence, the volume provides an unparalleled source of information about this area of medicine and will be helpful not just to practising clinicians but also to basic scientists researching in the field who need to familiarize themselves with the clinical problems.

First published in 1992, AY's Neuroanatomy of C. elegans for Computation provides the neural circuitry database of the nematode Caenorhabditis elegans, both in printed form and in ASCII files on 5.25-inch diskettes (for use on IBM (R) and compatible personal computers, Macintosh (R) computers, and higher level machines). Tables of connections among neuron classes, synapses among individual neurons, gap junctions among neurons, worm cells and their embryonic origin, and synthetically derived neuromuscular connections are presented together with the references from which the data were compiled and edited. Sample data files and source codes of FORTRAN and BASIC programs are provided to illustrate the use of mathematical tools for any researcher or student interested in examining a natural neural network and discovering what makes it tick.

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer's disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the last two decades. It brings together an elite group of 30 pioneering researchers. In writing about their own work, these scientists report on the cutting-edge investigations that are now being conducted across a variety of disciplines. This text is designed to aid researchers and inform those involved in the treatment and clinical aspects of a number of histamine-related diseases. Presents Several Disease-Specific Chapters Certainly, the most comprehensive and cutting-edge volume in the field, this text includes material drawn from groundbreaking research techniques and patent literature. Put together with great thought and passion, it is written to serve as a primary resource for anyone involved with or interested in the identification and localization of H3 receptors and the ligands being developed as therapeutic agents to treat a wide range of diseases including some that were once considered intractable.

Your ticket to acing Clinical Anatomy

Clinical anatomy is the study of human anatomy as it relates to clinical practice. Unlike a basic anatomy and physiology course designed to teach general anatomical knowledge, clinical anatomy focuses on specific structures and issues that people may encounter in a clinical setting.

"Clinical Anatomy For Dummies" presents a friendly, unintimidating overview of the material covered in a typical college-level Clinical Anatomy course. Clear definitions, concise explanations, and plenty of full-color illustrations make "Clinical Anatomy For Dummies" the most accessible book available to supplement your classroom texts.Plain-English explanations make difficult concepts easy to graspTracks to a typical college-level Clinical Anatomy courseFeatures a 16-page color insert

Whether you're a student or a practicing healthcare worker, "Clinical Anatomy for Dummies" makes this subject accessible and easy to grasp.

This book is dedicated to those who died of malignant hyperthermia and to their families. It contains cases studies that would be helpful for anesthesiologists, surgeons, physiologists, molecular biologists, biophysicists, biochemists, pathologists, students, and post doctoral fellows.

Edited by an expert team of researchers and clinicians, The Epidermis in Wound Healing combines current information with the latest research results to provide a complete picture of the latest advances in the field. Presenting the newest findings, the book focuses on biological advances that improve knowledge and lead to new opportunities for research and clinical applications. Topics include quantifying repair in the epidermis, physical and chemical factors affecting repair, new approaches to understanding and treating wounds, and the role of gene action in the epidermis during wound repair. A unique feature is the inclusion of a critical evaluation of current clinical practices.

Anaesthesiologists regularly administer potent, and potentially toxic, drugs that profoundly interfere with fundamental physiological functions such as breathing, cardiac output, blood pressure, the protective reflexes and the perception of pain. Reviewing all aspects of human physiology, Physiology for Anaesthesiologists provides a working knowledge of physiological principles and their application to anaesthesia and intensive care. The text covers the various systems of the human body, from the central nervous system to the liver and kidneys. The reader gains an understanding not only of each system discussed, but also of how each of those physiological systems interact with each other. The section on pain, for example, explains how the body warns of dysfunction in one or more systems. In addition to covering the core material for professional examinations, some topics not usually dealt with in textbooks for anaesthetists are also covered, such as the impact of anaesthesia and surgery on the immune system. Written in a clear and concise style, the book supplies up-to-date information to trainees in anaesthesiology and related specialities preparing for professional examinations: both editors have a wealth of experience in these subjects. The book also helps established anaesthesiologists, and those in other related specialities, who want to keep up with recent developments in the field.

Bundle includes: 9781119576488 Fundamentals of Anatomy and Physiology: For Nursing and Healthcare Students, 3rd Edition A concise yet comprehensive introduction to the structure and function of the human body. Written with the needs of nursing and healthcare students in mind, this best-selling textbook incorporates clinical examples and scenarios throughout to illustrate how the topics covered are applied in practice. Hundreds of full-colour illustrations complement numerous case studies encompassing all fields of nursing practice, alongside learning outcomes, self-assessment tests and other effective learning tools. 9781119699491 Fundamentals of Applied Pathophysiology: An Essential Guide for Nursing and Healthcare Students, 4th Edition A highly visual and accessible introduction to pathophysiology for nursing and healthcare students, including brand-new content on homeostasis, a systematic approach to assessment, and key terminology. The book features links to clinical observations, vital signs to observe, investigation boxes, clinical red flags, medication alerts, and the latest, contemporary evidence for care management, including National Early Warning Score 2 (NEWS2).

Multidisciplinary Anatomy & Physiology textbook for Health Professionals! This title will enable the reader to take an informed interest in the patient's or client's condition, and in the planning of total patient care or complementary therapy treatments. It is relevant to students studying anatomy and physiology at a basic level - nursing, complementary therapies, sport therapy, physiotherapy and occupational therapy. A systems approach is presented in an accessible way accompanied by clear illustrations. It is written in an easy to read style explaining otherwise complicated topics.

Functional Anatomy for Sport and Exercise: A Quick A-to-Z Reference is the most user-friendly and accessible available reference to human musculoskeletal anatomy in its moving, active context. Fully updated and revised, the second edition features more illustrations to enhance student learning and an expanded hot topics section to highlight key areas of research in sport and exercise. An accessible format makes it easy for students to locate clear, concise explanations and descriptions of anatomical structures, human movement terms and key concepts. Covering all major anatomical areas, the book includes: an A-to-Z guide to anatomical terms and concepts, from the head to the foot clear and detailed colour illustrations cross-referenced entries throughout hot topics discussed in more detail in sports examples discussed in more detail full references and suggested further reading This book is an essential quick reference for undergraduate students in applied anatomy, functional anatomy, kinesiology, sport and exercise science, physical education, strength and conditioning, biomechanics and athletic training.

Key features: High quality full color photographs and descriptive texts on the location and removal of the organs from the mouse Instructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysis Full color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achieved All in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader 'from the mouse to the microscope', it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.

An all-in-one illustrated guide to human anatomy with encyclopedic coverage from bones and muscles to systems and processes. This in-depth manual to the human body's physical structure, chemical workings, and potential problems is a must-have reference to help further your studies or knowledge of how our bodies work.

Each page of The Human Body Book, updated to reflect the latest medical advances, is illustrated with colourful and comprehensive diagrams, which are thoroughly annotated to take you right into the cells and fibres that are responsible for keeping the human body ticking.

The opening chapter, Integrated Body, explains how the parts of the body work together at various levels of size and hierarchy to produce the living whole. It also contains an overview of the major body systems, enlivened by real-life 3D medical scans of the entire body. The chapters that follow provide coverage of the body function by function, system by system. Eleven main body systems are covered in turn, with each section ending on common injuries, diseases, and disorders afflicting that system. The book concludes with a chapter on Growth and Development which looks in detail at how the body changes over the course of a human lifespan.

Neuroanatomy through Clinical Cases is widely acclaimed for bringing a pioneering interactive approach to the teaching of neuroanatomy. The book uses over 100 actual clinical cases and high-quality radiologic images to bring the subject to life. The third edition is fully updated with the latest advances in the field, and includes several exciting new cases. This approach allows students to appreciate the clinical relevance of structural details as they are being learned, and to integrate knowledge of disparate functional systems, so the practical knowledge of neuroanatomy is not soon forgotten.

Perfect for reinforcing knowledge in any level histology course, Netter's Histology Cut-Out Flash Cards, 2nd Edition, offer a convenient and portable histology review - including gross anatomy and histopathology for today's integrated courses and even more clinical relevance. User-friendly and engaging to use, these 200 superbly illustrated cards increase your understanding of important structures and reinforce your understanding of how the human body works in health as well as illness and injury. Printed deck includes perforated guides for cutting each page into four cards: image on front, answers and concise text on back. Prepunched holes are perfect for looping on a ring or keychain for study anytime, anywhere. Microscopic features of cells, tissues, and organs are clearly depicted with classic Netter anatomy illustrations and extensive additional images including histology slides and light and electron micrographs. More basic principles, clinical correlations, and histopathology content prepares you for commonly tested topics on board exams. Master the histology knowledge you need to know by using these flash cards in conjunction with Netter's Essential Histology, 3rd Edition, also by Drs. Ovalle and Nahirney. The cards are cross referenced to the text, making it easy to find more in-depth information on any topic. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Aimed at the medical and dental student this manual presents a regional approach to anatomy which is in contrast to the systematic approach preferred by the health care sciences such as nursing, occupational therapy, and physiotherapy. The authors attempt to comply with the specific clinical needs of the medical and dental undergraduate student by concentrating on applicable clinical anatomy. The curriculum is presented on such a level that postgraduate students, who need to maintain a thorough overview in regions other than that of their specific speciality, will also benefit.