This text offers comprehensive coverage of a wide range of concepts related to articulation and phonology. The text's strong, clinical emphasis along with the variety of helpful learning aids makes this text ideal for understanding critical topics. In this comprehensive fourth edition of Articulatory and Phonological Impairments: A Clinical Focus, a range of topics are covered including, an overview of phonetic transcription and diacritics used to document disordered speech, several theoretical models, including newer nonlinear frameworks, phonological development, and relevant diagnostic and therapeutic suggestions for special populations discussed in detail. Additionally, the application of theoretical principles to practical examples creates a bridge for students between conceptual learning and the understanding of principles based on their application. These topics, coupled with the learning aids throughout the text, strengthen the conceptual framework and through application, demonstrate that the student has understood specific principles.A large portion of the text is devoted to specific assessment and treatment details of articulatory and phonological disorders including a section on childhood apraxia of speech, cerebral palsy, cleft lip and palate, mental disability, hearing impairments, acquired dysarthrias, and apraxia of speech. These topics are encompassed in a clinical framework which continues to provide practical examples and the application of principles to real-life situations.

First published in 1992, AY's Neuroanatomy of C. elegans for Computation provides the neural circuitry database of the nematode Caenorhabditis elegans, both in printed form and in ASCII files on 5.25-inch diskettes (for use on IBM (R) and compatible personal computers, Macintosh (R) computers, and higher level machines). Tables of connections among neuron classes, synapses among individual neurons, gap junctions among neurons, worm cells and their embryonic origin, and synthetically derived neuromuscular connections are presented together with the references from which the data were compiled and edited. Sample data files and source codes of FORTRAN and BASIC programs are provided to illustrate the use of mathematical tools for any researcher or student interested in examining a natural neural network and discovering what makes it tick.

This detailed volume for the first time explores techniques and protocols involving quantitative imaging flow cytometry (IFC), which has revolutionized our ability to analyze cells, cellular clusters, and populations in a remarkable fashion. Beginning with an introduction to technology, the book continues with sections addressing protocols for studies on the cell nucleus, nucleic acids, and FISH techniques using an IFC instrument, immune response analysis and drug screening, IFC protocols for apoptosis and cell death analysis, as well as morphological analysis and the identification of rare cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Imaging Flow Cytometry: Methods and Protocols will be a critical source for all laboratories seeking to implement IFC in their research studies.

Acquire the 21st-century skills to succeed in A&P with a leading text in the field. Human Anatomy & Physiology, 12th edition by best-selling authors Elaine Marieb and Katja Hoehn is one of the leading texts in the field, aimed not only to support your learning every step of the way but also to motivate and inspire you as a future scientist in the field. An ideal learning resource both for novice and expert students, this text will equip you with the most up to date, 21st-century skills to succeed in A&P and beyond. Well-known for its engaging, conversational writing style, easy-to-follow figures, and unique clinical insights, this editioncontinues its tradition of innovation, with an array of compelling multimedia tools and visual presentations, along with questions and clinical case studies to cement your understanding of the topics. With this text you can: Master the challenging A&P terminology Practice your critical thinking and problem-solving skills Apply your knowledge to clinical scenarios Gain the knowledge required for entry into nursing, allied health, and exercise science programs. Personalise your learning experience and improve results with Mastering (R) A&P. Mastering provides access to trusted content using customisable tools, features, and assessments built for today's digital learners. Pearson Mastering (R) A&P is not included. If you would like to purchase both the physical text and Mastering A&P, search for: 9781292421957 Human Anatomy & Physiology, Global Edition, 12th edition with Mastering Biology The bundle consists of: 9781292421803 Human Anatomy & Physiology, Global Edition, 12th Edition 9781292421797 Pearson Mastering A&P- Instant Access - for Human Anatomy & Physiology, Global Edition 9781292421742 Pearson Mastering A&P with Pearson eText - Instant Access - for Human Anatomy & Physiology, Global Edition Mastering A&P should only be purchased when required by an instructor. Please be sure you have the correct ISBN and Course ID. Instructors, contact your Pearson representative for more information.

The aim of Mechano-Electric Correlations in the Human Physiological System is to present the mechanical and electrical properties of human soft tissues and the mathematical models related to the evaluation of these properties in time, as well as their biomedical applications. This book also provides an overview of the bioelectric signals of soft tissues from various parts of the human body. In addition, this book presents the basic dielectric and viscoelastic characteristics of soft tissues, an introduction to the measurement and characteristics of bioelectric signals and their relationship with the mechanical activity, electromyography and the correlation of electromyograms with the muscle activity in normal and certain clinical conditions. The authors also present a case study on the effect of lymphatic filariasis on the mechanical and electrical activity of the muscle. Features: Explains the basics of electrical and mechanical properties of soft tissues in time and frequency domain along with the mathematical models of soft tissue mechanics Explores the correlation of electrical properties with the mechanical properties of biological soft tissues using computational techniques Provides a detailed introduction to electrophysiological signals along with the types, applications, properties, problems and associated mathematical models Explains the electromechanics of muscles using electromyography recordings from various muscles of the human physiological system Presents a case study on the effect of lymphatic filariasis on the mechanical and electrical activity of the muscle Mechano-Electric Correlations in the Human Physiological System is intended for biomedical engineers, researchers and medical scientists as well graduate and undergraduate students working on the mechanical properties of soft tissues.

The Physiological Measurement Handbook presents an extensive range of topics that encompass the subject of measurement in all departments of medicine. The handbook describes the use of instruments and techniques for practical measurements required in medicine. It covers sensors, techniques, hardware, and software as well as information on processing systems, automatic data acquisition, reduction and analysis, and their incorporation for diagnosis. Suitable for both instrumentation designers and users, the handbook enables biomedical engineers, scientists, researchers, students, health care personnel, and those in the medical device industry to explore the different methods available for measuring a particular physiological variable. It helps readers select the most suitable method by comparing alternative methods and their advantages and disadvantages. In addition, the book provides equations for readers focused on discovering applications and solving diagnostic problems arising in medical fields not necessarily in their specialty. It also includes specialized information needed by readers who want to learn advanced applications of the subject, evaluative opinions, and possible areas for future study.

Tried and true - build A&P confidence every step of the way! Here's the approach that makes A&P easier to master. A student-friendly writing style, superb art program, and learning opportunities in every chapter build a firm foundation in this must-know subject to ensure success. See what students are saying online… Great book! "This is THE best Anatomy & Physiology book I've ever used. Clear and easy to understand. Some of the areas of physiology I've had problems with in the past were made clear this term with this book! I had to have it for class of course, but I'd also read it for fun. (I plan to keep the book instead of sell it)" - A. Francis Good. "This was a great text for my Anatomy and Physiology class. It was easy to understand and I got a great grade." - Alisa M. Also Available: Student Workbook for Essentials of Anatomy and Physiology, 8th Edition

With the most extensive, comprehensive collection of anatomy multiple-choice questions in strict, current USMLE format, Gray's Anatomy Review, 3rd Edition, is an easy-to-use study tool that helps you relate anatomy to clinical practice and pass your exams. Whether used as a companion to Gray's Anatomy for Students or as a stand-alone resource, this medical textbook is your indispensable review book for both in-course examinations and the USMLE Step 1. Includes more than 1,400 high-yield questions, mirroring the USMLE Step 1 and complete with answers and rationales, that challenge your grasp of anatomical knowledge and the anatomical basis of disease. Features a new neuroanatomy chapter containing approximately 100 all-new questions that cover key concepts and relate them to clinical practice. Groups questions more logically within chapters for more effective study, first within topic areas and then from easy to more difficult. Provides specific, updated page references to current editions of Gray's Anatomy for Students, plus key answers and explanations to Gray's Basic Anatomy and Gray's Atlas of Anatomy for additional review. Helps you visualize key concepts with updated radiographic and ultrasound images and extensive use of photographs. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access interactive quizzes, plus all of the text, figures, and references from the book on a variety of devices.

Your Body, Your Yoga goes beyond any prior yoga anatomy book available. It looks not only at the body's unique anatomical structures and what this means to everyone's individual range of motion, but also examines the physiological sources of restrictions to movement. Two volumes are provided in this book: Volume 1 raises a new mantra to be used in every yoga posture: What Stops Me? The answers presented run through a spectrum, beginning with a variety of tensile resistance to three kinds of compressive resistance. Examined is the nature of muscles, fascia, tendons, ligaments, joint capsules, bones and our extracellular matrix and their contribution to mobility. The shape of these structures also defines our individual, ultimate range of movement, which means that not every body can do every yoga posture. The reader will discover where his or her limits lie, which dictates which alignment cues will work best, and which ones should be abandoned. Volume 2 will take these principles and apply them to the lower body, examining the hip joint, the knee, ankle and foot, and will present how your unique variations in these joints will show up in your yoga practice.

This is the ninth of 15 short atlases reimagining the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition focuses on the second trimester of human brain development. Serial sections from specimens between 160mm and 170mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human central nervous system development. Key Features • Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Intended for neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change.

Thoroughly revised and updated to reflect key advances in behavioral neurology, "Neurobehavioral Anatomy, Third Edition" is a clinically based account of the neuroanatomy of human behavior centered on a consideration of behavioral dysfunction caused by disorders of the brain. A concise introduction to brain-behavior relationships that enhances patient care and assists medical students, the book also serves as a handy reference to researchers, neuroscientists, psychiatrists, and geriatricians.

The book outlines how cognitive and emotional functions are represented and organized in the brain to produce the behaviors regarded as uniquely human. It reviews the effects of focal and diffuse brain lesions, and from this analysis a conception of the normal operations of the healthy brain emerges. Christopher M. Filley integrates data and material from different disciplines to create a concise and accessible synthesis that informs the clinical understanding of brain-behavior relationships. Clinically practical and theoretically stimulating, the book is an invaluable resource for those involved in the clinical care and study of people with neurobehavioral disorders.

Including a useful glossary and extensive references guiding users to further research, the third edition will be of significance to medical students, residents, fellows, practicing physicians, and the general reader interested in neurology.

This tenth of 15 short atlases reimagines the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition focuses on the second trimester of human brain development. Serial sections from specimens between 190mm and 210mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human CNS development. Key Features • Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Appeals to neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change

• Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Intended for neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change.

Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.

The Geometric Induction of Bone Formation describes new biomimetic biomaterials that offer mechanistic osteogenic surfaces for the autonomous and spontaneous induction of bone formation without the addition of osteogenic soluble molecular signals of the transforming growth factor- supergene family. The chapters frame our understanding of regenerative medicine in primate species, including humans. The goal is to unravel the fundamental biological mechanisms of bone formation unique to non-human and human primates. The broad target audience dovetails with several disciplines both in the academic and private biotech sectors primarily involved in molecular biology, tissue biology, tissue engineering, biomaterial science, and reconstructive, orthopedic, plastic, and dental surgery. Key Features Includes outstanding images of undecalcified whole mounted sections Summarizes non-human primate research - ideal for clinical translation Reviews methods for creating devices capable of making bone autonomously, i.e. an intrinsically osteo-inductive bioreactor and/or biomaterial Describes the spontaneous induction of bone formation including a whole spectrum of tissue biology, from basic molecular biology to clear-cut morphology and pre-clinical application in non-human primate species Intended for audiences in both academic research and the biotech industry

This atlas provides all the basic and advanced information required by surgeons in order to understand fully the skull base anatomy. It is organized according to anatomo-surgical pathways to the hidden areas of the skull base. These pathways are described in step-by-step fashion with the aid of a wealth of color images and illustrations. The emphasis is on endoscopic anatomy, but in order to provide a holistic perspective, informative three-dimensional reconstructions are presented alongside the endoscopic images and radiologic images are included when appropriate. In effect, windows are opened on the anatomy so that the reader is guided on a journey throughout the skull base region. This anatomically oriented atlas will serve as an ideal learning tool for novice surgeons and will also prove an invaluable reference for the more experienced surgeon

This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. Finally, an up-to-date review of human diseases associated with heme synthesis and application of heme synthesis in photodynamic therapy in cancer treatment is presented.Heme biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to comprehend the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.

Combining detailed descriptions of pelvic anatomy with easy-to-follow instructions for gynecologic procedures, Atlas of Pelvic Anatomy and Gynecologic Surgery, 5th Edition, is a comprehensive, up-to-date atlas that reflects current practices in this fast-changing field. Pelvic anatomy and surgical operations are depicted through full-color anatomic drawings, correlative surgical artwork with step-by-step photographs, and computer-assisted hybrid photo illustrations. Complete coverage of both conventional and endoscopic surgeries helps you master the full spectrum of surgical procedures. Covers all frequently performed gynecologic operations including laparotomy, laparoscopic, robotic, hysteroscopic, vaginal, vulvar, and cystoscopic procedures. Includes expanded sections on gender reassignment surgery and vulvar and cervical surgery, as well as a new chapter devoted to laparoscopic techniques. Contains a revised anatomic section with updated figures, plus high-quality artwork and clinical photographs throughout-now entirely in full color. Features numerous videos of surgeries and cadaver dissection. Ideal for practicing obstetricians-gynecologists, obstetrics-gynecology residents, general surgeons, subspecialists, nurses, and medical students with an interest in gynecology. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

Thoroughly researched using experimentation and re-examination of all previously published evidence, Molecular and Physiological Mechanisms of Muscle Contraction is a carefully crafted treatise and revision of previous conceptions of muscle contraction. It presents detailed descriptions of new, previously unpublished data and hybrids recent findings with the standard Huxley model. This book demonstrates that traditional concepts cannot fully explain contraction and builds upon previous work. It identifies flaws in the reasoning initially used to explain some results as well as alternative interpretations accounting for inconsistencies. In response to previous bodies of inconsistent or conflicting theories and data, the book synthesizes research based on the Huxley model with more recent experimental and laboratory findings to define a new model. The new model this book proposes is not a replacement for the standard Huxley model of muscle contraction, but a modification based on recent research and synthesized with pre-existing data and conceptions. It reconciles new data with prior information that is contradictory or not entirely explicable in proposing a new integrated and more complete model of muscle contraction.

This is the ninth of 15 short atlases reimagining the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition focuses on the second trimester of human brain development. Serial sections from specimens between 160mm and 170mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human central nervous system development. Key Features • Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Intended for neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change.

Acquire the 21st-century skills to succeed in A&P with a leading text in the field. Human Anatomy & Physiology, 12th edition by best-selling authors Elaine Marieb and Katja Hoehn is one of the leading texts in the field, aimed not only to support your learning every step of the way but also to motivate and inspire you as a future scientist in the field. An ideal learning resource both for novice and expert students, this text will equip you with the most up to date, 21st-century skills to succeed in A&P and beyond. Well-known for its engaging, conversational writing style, easy-to-follow figures, and unique clinical insights, this editioncontinues its tradition of innovation, with an array of compelling multimedia tools and visual presentations, along with questions and clinical case studies to cement your understanding of the topics. With this text you can: Master the challenging A&P terminology Practice your critical thinking and problem-solving skills Apply your knowledge to clinical scenarios Gain the knowledge required for entry into nursing, allied health, and exercise science programs. Personalise your learning experience and improve results with Mastering (R) A&P. Mastering provides access to trusted content using customisable tools, features, and assessments built for today's digital learners. Pearson Mastering (R) A&P is not included. If you would like to purchase both the physical text and Mastering A&P, search for: 9781292421957 Human Anatomy & Physiology, Global Edition, 12th edition with Mastering Biology The bundle consists of: 9781292421803 Human Anatomy & Physiology, Global Edition, 12th Edition 9781292421797 Pearson Mastering A&P- Instant Access - for Human Anatomy & Physiology, Global Edition 9781292421742 Pearson Mastering A&P with Pearson eText - Instant Access - for Human Anatomy & Physiology, Global Edition Mastering A&P should only be purchased when required by an instructor. Please be sure you have the correct ISBN and Course ID. Instructors, contact your Pearson representative for more information.

This volume provides an updated collection of protocols for manipulating and studying VEGF signaling pathways in vitro and in vivo and aims to present a range of both firmly established and newly emerging technologies. Covering multiple model species, from mouse to zebrafish to human, the book explores the role of VEGF and VEGFR isoforms in exosomes, cultured cells, or in tissues, as well as robust cell assays for the investigation of basic angiogenic mechanisms and VEGF signaling in more complex cellular systems, amongst other subjects. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, VEGF Signaling: Methods and Protocols, Second Edition provides a useful tool for researchers in the vascular biology community and beyond in understanding the basic biology of VEGF signaling and in translating this research into the clinic.